A 3D human liver model of nonalcoholic steatohepatitis

Background and Aims: To better understand nonalcoholic steatohepatitis (NASH) disease progression and to evaluate drug targets and compound activity, we undertook the development of an in vitro 3D model to mimic liver architecture and the NASH environment.

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Bibliographic Details
Main Authors: Duriez, Marion (Author) , Jacquet, Agnes (Author) , Hoet, Lucile (Author) , Roche, Sandrine (Author) , Bock, Marie-Dominique (Author) , Rocher, Corinne (Author) , Haussy, Gilles (Author) , Vigé, Xavier (Author) , Bocskei, Zsolt (Author) , Slavnic, Tamara (Author) , Martin, Valérie (Author) , Guillemot, Jean-Claude (Author) , Didier, Michel (Author) , Kannt, Aimo (Author) , Orsini, Cécile (Author) , Mikol, Vincent (Author) , Fèvre, Anne-Céline Le (Author)
Format: Article (Journal) Editorial
Language:English
Published: 2020
In: Journal of clinical and translational hepatology
Year: 2020, Volume: 8, Issue: 4, Pages: 359-370
ISSN:2310-8819
DOI:10.14218/JCTH.2020.00015
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.14218/JCTH.2020.00015
Verlag, kostenfrei, Volltext: http://www.xiahepublishing.com/2310-8819/ArticleFullText.aspx?sid=2&id=10.14218%2fJCTH.2020.00015
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Author Notes:Marion Duriez, Agnes Jacquet, Lucile Hoet, Sandrine Roche, Marie-Dominique Bock, Corinne Rocher, Gilles Haussy, Xavier Vigé, Zsolt Bocskei, Tamara Slavnic, Valérie Martin, Jean-Claude Guillemot, Michel Didier, Aimo Kannt, Cécile Orsini, Vincent Mikol and Anne-Céline Le Fèvre
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Summary:Background and Aims: To better understand nonalcoholic steatohepatitis (NASH) disease progression and to evaluate drug targets and compound activity, we undertook the development of an in vitro 3D model to mimic liver architecture and the NASH environment.
Item Description:Gesehen am 31.03.2025
Physical Description:Online Resource
ISSN:2310-8819
DOI:10.14218/JCTH.2020.00015