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Guidelines of Onkopedia: what is new?: Locally advanced rectal cancer : guidelines

This article briefly summarizes clinically relevant new aspects of the recently published German, Austrian, and Swiss Onkopedia guideline for the treatment of locally advanced rectal cancer. Main aspects comprise (i) the use of total neoadjuvant therapy for rectal cancers with high-risk features, (i...

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Main Authors: Hofheinz, Ralf-Dieter (Author) , Arnold, Dirk (Author) , Borner, Markus (Author) , Eisterer, Wolfgang (Author) , Folprecht, Gunnar (Author) , Ghadimi, Michael (Author) , Graeven, Ullrich (Author) , Grünberger, Birgit (Author) , Hebart, Holger (Author) , Hegewisch-Becker, Susanna (Author) , Heinemann, Volker (Author) , Pritzkuleit, Ron (Author) , Rödel, Claus (Author) , Rumpold, Holger (Author) , Trarbach, Tanja (Author) , Maschmeyer, Georg (Author) , Wörmann, Bernhard (Author)
Format: Article (Journal)
Language:English
Published: December 2024
In: Oncology research and treatment
Year: 2024, Volume: 47, Issue: 12, Pages: 610-614
ISSN:2296-5262
DOI:10.1159/000541376
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1159/000541376
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Author Notes:Ralf-Dieter Hofheinz, Dirk Arnold, Markus Borner, Wolfgang Eisterer, Gunnar Folprecht, Michael Ghadimi, Ullrich Graeven, Birgit Grünberger, Holger Hebart, Susanna Hegewisch-Becker, Volker Heinemann, Ron Pritzkuleit, Claus Rödel, Holger Rumpold, Tanja Trarbach, Georg Maschmeyer, Bernhard Wörmann
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Summary:This article briefly summarizes clinically relevant new aspects of the recently published German, Austrian, and Swiss Onkopedia guideline for the treatment of locally advanced rectal cancer. Main aspects comprise (i) the use of total neoadjuvant therapy for rectal cancers with high-risk features, (ii) treatment with neoadjuvant chemotherapy for patients with a low risk for local recurrence, (iii) immunotherapy using dostarlimab in patients with MSI high/dMMR rectal cancer, as well as (iv) the implementation of organ sparing treatment concepts. The availability of several evidence-based treatment options requires intensive discussion within the multidisciplinary team as well as dedicated information for patients about treatment goals, options, and risks of individual treatment approaches.
Item Description:Online veröffentlicht: 9. Oktober 2024
Gesehen am 08.04.2025
Physical Description:Online Resource
ISSN:2296-5262
DOI:10.1159/000541376

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