Emotion regulation in self-injurious youth: a tale of two circuits
Two emotion regulation (ER) networks, the amygdala and ventral striatum (VS) circuits underpin defensive and reward processes related to non-suicidal self-injury (NSSI). Youth who engaged in non-suicidal self-injury behavior (NSSIB) and healthy controls either watched images passively (passive condi...
Gespeichert in:
| Hauptverfasser: | , , , , , , , , , , , |
|---|---|
| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
2025
|
| In: |
Psychiatry research. Neuroimaging
Year: 2025, Jahrgang: 347, Pages: 1-12 |
| ISSN: | 1872-7506 |
| DOI: | 10.1016/j.pscychresns.2024.111944 |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1016/j.pscychresns.2024.111944 Verlag, lizenzpflichtig, Volltext: https://www.sciencedirect.com/science/article/pii/S0925492724001677 
|
| Verfasserangaben: | Carmen Santana-Gonzalez, Janani Ranatunga, Giang Nguyen, Brianna Greiskalns, Natasha Das, Evan Lattimer, Matthew Maurice, Gina Yi, Anna-Lena Zietlow, Monika Eckstein, Anna Zilverstand, Karina Quevedo |
MARC
| LEADER | 00000caa a2200000 c 4500 | ||
|---|---|---|---|
| 001 | 1923194976 | ||
| 003 | DE-627 | ||
| 005 | 20250717010630.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 250417s2025 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1016/j.pscychresns.2024.111944 |2 doi | |
| 035 | |a (DE-627)1923194976 | ||
| 035 | |a (DE-599)KXP1923194976 | ||
| 035 | |a (OCoLC)1528044780 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 11 |2 sdnb | ||
| 100 | 1 | |a Santana-Gonzalez, Carmen |e VerfasserIn |0 (DE-588)1363323814 |0 (DE-627)1923197223 |4 aut | |
| 245 | 1 | 0 | |a Emotion regulation in self-injurious youth |b a tale of two circuits |c Carmen Santana-Gonzalez, Janani Ranatunga, Giang Nguyen, Brianna Greiskalns, Natasha Das, Evan Lattimer, Matthew Maurice, Gina Yi, Anna-Lena Zietlow, Monika Eckstein, Anna Zilverstand, Karina Quevedo |
| 264 | 1 | |c 2025 | |
| 300 | |b Illustrationen, Diagramme | ||
| 300 | |a 12 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Online veröffentlicht: 18. Dezember 2024 | ||
| 500 | |a Gesehen am 17.04.2025 | ||
| 520 | |a Two emotion regulation (ER) networks, the amygdala and ventral striatum (VS) circuits underpin defensive and reward processes related to non-suicidal self-injury (NSSI). Youth who engaged in non-suicidal self-injury behavior (NSSIB) and healthy controls either watched images passively (passive condition) or increased their positive affect during positive/neutral images and decreased their negative affect during negative and self-harm images (regulate condition) in the scanner. NSSI youth showed higher amygdala to precuneus and inferior parietal lobe (IPL) connectivity while regulating emotions during self-harm images, a pattern which was associated with higher self-injury frequency. NSSI youth showed higher VS connectivity to the fusiform gyrus and parahippocampus while regulating emotions elicited by self-harm and positive images, which was in turn linked to higher self-harm frequency and relief after NSSI. Higher amygdala-precuneus and IPL connectivity in NSSI youth suggest greater self-identification with, or difficulty regulating negative affect elicited by, self-injury images. High VS-fusiform gyrus and parahippocampus connectivity during positive and self-harm images implies reward anomalies and/or greater effort to regulate positive affect. VS circuit's’ links to relief and NSSIB frequency suggest VS reward-based learning as biomarker of NSSIB endurance. We discovered ER mechanisms in adolescents with NSSIB and promising targets for effective NSSIB treatment. | ||
| 650 | 4 | |a Amygdala | |
| 650 | 4 | |a Emotion regulation | |
| 650 | 4 | |a Functional connectivity | |
| 650 | 4 | |a Relief | |
| 650 | 4 | |a Self-harm | |
| 650 | 4 | |a Self-injury | |
| 650 | 4 | |a Ventral striatum | |
| 700 | 1 | |a Ranatunga, Janani |e VerfasserIn |4 aut | |
| 700 | 1 | |a Nguyen, Giang |e VerfasserIn |4 aut | |
| 700 | 1 | |a Greiskalns, Brianna |e VerfasserIn |4 aut | |
| 700 | 1 | |a Das, Natasha |e VerfasserIn |4 aut | |
| 700 | 1 | |a Lattimer, Evan |e VerfasserIn |4 aut | |
| 700 | 1 | |a Maurice, Matthew |e VerfasserIn |4 aut | |
| 700 | 1 | |a Yi, Gina |e VerfasserIn |4 aut | |
| 700 | 1 | |a Zietlow, Anna-Lena |e VerfasserIn |0 (DE-588)1074049675 |0 (DE-627)830218270 |0 (DE-576)435561073 |4 aut | |
| 700 | 1 | |a Eckstein, Monika |e VerfasserIn |0 (DE-588)1072057204 |0 (DE-627)826820778 |0 (DE-576)433516437 |4 aut | |
| 700 | 1 | |a Zilverstand, Anna |e VerfasserIn |4 aut | |
| 700 | 1 | |a Quevedo, Karina |e VerfasserIn |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Psychiatry research. Neuroimaging |d Amsterdam : Elsevier, 1990 |g 347(2025), Artikel-ID 111944, Seite 1-12 |h Online-Ressource |w (DE-627)894201530 |w (DE-600)2900605-3 |w (DE-576)491161778 |x 1872-7506 |7 nnas |a Emotion regulation in self-injurious youth a tale of two circuits |
| 773 | 1 | 8 | |g volume:347 |g year:2025 |g elocationid:111944 |g pages:1-12 |g extent:12 |a Emotion regulation in self-injurious youth a tale of two circuits |
| 856 | 4 | 0 | |u https://doi.org/10.1016/j.pscychresns.2024.111944 |x Verlag |x Resolving-System |z lizenzpflichtig |3 Volltext |
| 856 | 4 | 0 | |u https://www.sciencedirect.com/science/article/pii/S0925492724001677 |x Verlag |z lizenzpflichtig |3 Volltext |
| 951 | |a AR | ||
| 992 | |a 20250417 | ||
| 993 | |a Article | ||
| 994 | |a 2025 | ||
| 998 | |g 1072057204 |a Eckstein, Monika |m 1072057204:Eckstein, Monika |d 910000 |d 910600 |d 50000 |e 910000PE1072057204 |e 910600PE1072057204 |e 50000PE1072057204 |k 0/910000/ |k 1/910000/910600/ |k 0/50000/ |p 10 | ||
| 998 | |g 1074049675 |a Zietlow, Anna-Lena |m 1074049675:Zietlow, Anna-Lena |d 50000 |e 50000PZ1074049675 |k 0/50000/ |p 9 | ||
| 999 | |a KXP-PPN1923194976 |e 4706597846 | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"name":{"displayForm":["Carmen Santana-Gonzalez, Janani Ranatunga, Giang Nguyen, Brianna Greiskalns, Natasha Das, Evan Lattimer, Matthew Maurice, Gina Yi, Anna-Lena Zietlow, Monika Eckstein, Anna Zilverstand, Karina Quevedo"]},"recId":"1923194976","note":["Online veröffentlicht: 18. Dezember 2024","Gesehen am 17.04.2025"],"person":[{"role":"aut","given":"Carmen","display":"Santana-Gonzalez, Carmen","family":"Santana-Gonzalez"},{"given":"Janani","display":"Ranatunga, Janani","family":"Ranatunga","role":"aut"},{"display":"Nguyen, Giang","family":"Nguyen","given":"Giang","role":"aut"},{"role":"aut","display":"Greiskalns, Brianna","family":"Greiskalns","given":"Brianna"},{"given":"Natasha","family":"Das","display":"Das, Natasha","role":"aut"},{"given":"Evan","display":"Lattimer, Evan","family":"Lattimer","role":"aut"},{"role":"aut","display":"Maurice, Matthew","family":"Maurice","given":"Matthew"},{"role":"aut","given":"Gina","display":"Yi, Gina","family":"Yi"},{"display":"Zietlow, Anna-Lena","family":"Zietlow","given":"Anna-Lena","role":"aut"},{"role":"aut","family":"Eckstein","display":"Eckstein, Monika","given":"Monika"},{"given":"Anna","family":"Zilverstand","display":"Zilverstand, Anna","role":"aut"},{"family":"Quevedo","display":"Quevedo, Karina","given":"Karina","role":"aut"}],"title":[{"subtitle":"a tale of two circuits","title":"Emotion regulation in self-injurious youth","title_sort":"Emotion regulation in self-injurious youth"}],"physDesc":[{"extent":"12 S.","noteIll":"Illustrationen, Diagramme"}],"relHost":[{"note":["Gesehen am 24.03.2023"],"pubHistory":["Volume 35, issue 1 (1990)-"],"recId":"894201530","disp":"Emotion regulation in self-injurious youth a tale of two circuitsPsychiatry research. Neuroimaging","title":[{"title":"Psychiatry research","partname":"Neuroimaging : the official publication of the International Society for Neuroimaging in Psychiatry","title_sort":"Psychiatry research"}],"physDesc":[{"extent":"Online-Ressource"}],"part":{"extent":"12","year":"2025","volume":"347","text":"347(2025), Artikel-ID 111944, Seite 1-12","pages":"1-12"},"id":{"eki":["894201530"],"issn":["1872-7506"],"zdb":["2900605-3"]},"type":{"bibl":"periodical","media":"Online-Ressource"},"language":["eng"],"origin":[{"publisherPlace":"Amsterdam","dateIssuedDisp":"[1990]-","publisher":"Elsevier"}]}],"type":{"media":"Online-Ressource","bibl":"article-journal"},"id":{"eki":["1923194976"],"doi":["10.1016/j.pscychresns.2024.111944"]},"language":["eng"],"origin":[{"dateIssuedDisp":"2025","dateIssuedKey":"2025"}]} | ||
| SRT | |a SANTANAGONEMOTIONREG2025 | ||