Cover Image

Women with IBD show higher psychophysiological burden in comparison to men with IBD

Background: Inflammatory bowel disease (IBD) remains an incurable illness. Patients with IBD show gender-specific differences in various aspects of the disease. There is still uncertainty about the causality of the differences. Methods: The aim of this study was to determine the most relevant psycho...

Full description

Saved in:
Bibliographic Details
Main Authors: Schulz, Franziska (Author) , Foldenauer, Ann Christina (Author) , Weidmann, Lara (Author) , Thomann, Anne K. (Author) , Tal, Andrea Oliver (Author) , Plachta-Danielzik, Sandra (Author) , Krause, Thomas (Author) , Bokemeyer, Bernd (Author) , Zeuzem, Stefan (Author) , Kubesch, Alica (Author) , Blumenstein, Irina (Author)
Format: Article (Journal)
Language:English
Published: 20 December 2024
In: Journal of Clinical Medicine
Year: 2024, Volume: 13, Issue: 24, Pages: 1-9
ISSN:2077-0383
DOI:10.3390/jcm13247806
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.3390/jcm13247806
Verlag, kostenfrei, Volltext: https://www.mdpi.com/2077-0383/13/24/7806
Get full text
Author Notes:Franziska Schulz, Ann Christina Foldenauer, Lara Weidmann, Anne Kerstin Thomann, Andrea Oliver Tal, Sandra Plachta-Danielzik, Thomas Krause, Bernd Bokemeyer, Stefan Zeuzem, Alica Kubesch and Irina Blumenstein
Description
Summary:Background: Inflammatory bowel disease (IBD) remains an incurable illness. Patients with IBD show gender-specific differences in various aspects of the disease. There is still uncertainty about the causality of the differences. Methods: The aim of this study was to determine the most relevant psychophysiological gender-specific differences in IBD. For this purpose, a questionnaire survey was conducted on disease activity and psychological concomitant diseases in patients with IBD (n = 300). Among the 218 patients with IBD who provided gender information, both genders were equally distributed. Results: Females with IBD are significantly more affected by IBD-related symptoms than men. Disease activity Scores Harvey-Bradshaw Index (HBI), Partial Mayo Score (pMAYO) showed no significant differences between the sexes in the subgroups with CD (HBI, m: 3 (IQR 1-6), w: 4 (IQR 2-8), p = 0.0677) and UC (pMAYO, m: 1 (IQR 0-4), w: 3 (IQR 0-5), p = 0.2118). IBD Questionnaire (IBDQ)shows significant differences in the gender-specific analysis. The mean value of the IBDQ total score of the female participants was 4.4 (SD 1.1) and that of men was 5.0 (SD 1.0) (p = 0.0002). Conclusions: There is a great need to investigate the causality of gender-specific differences in greater depth.
Item Description:Gesehen am 22.04.2025
Physical Description:Online Resource
ISSN:2077-0383
DOI:10.3390/jcm13247806

Similar Items