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Women with IBD show higher psychophysiological burden in comparison to men with IBD

Background: Inflammatory bowel disease (IBD) remains an incurable illness. Patients with IBD show gender-specific differences in various aspects of the disease. There is still uncertainty about the causality of the differences. Methods: The aim of this study was to determine the most relevant psycho...

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Hauptverfasser: Schulz, Franziska (VerfasserIn) , Foldenauer, Ann Christina (VerfasserIn) , Weidmann, Lara (VerfasserIn) , Thomann, Anne K. (VerfasserIn) , Tal, Andrea Oliver (VerfasserIn) , Plachta-Danielzik, Sandra (VerfasserIn) , Krause, Thomas (VerfasserIn) , Bokemeyer, Bernd (VerfasserIn) , Zeuzem, Stefan (VerfasserIn) , Kubesch, Alica (VerfasserIn) , Blumenstein, Irina (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 20 December 2024
In: Journal of Clinical Medicine
Year: 2024, Jahrgang: 13, Heft: 24, Pages: 1-9
ISSN:2077-0383
DOI:10.3390/jcm13247806
Online-Zugang:Verlag, kostenfrei, Volltext: https://doi.org/10.3390/jcm13247806
Verlag, kostenfrei, Volltext: https://www.mdpi.com/2077-0383/13/24/7806
Volltext
Verfasserangaben:Franziska Schulz, Ann Christina Foldenauer, Lara Weidmann, Anne Kerstin Thomann, Andrea Oliver Tal, Sandra Plachta-Danielzik, Thomas Krause, Bernd Bokemeyer, Stefan Zeuzem, Alica Kubesch and Irina Blumenstein
Beschreibung
Zusammenfassung:Background: Inflammatory bowel disease (IBD) remains an incurable illness. Patients with IBD show gender-specific differences in various aspects of the disease. There is still uncertainty about the causality of the differences. Methods: The aim of this study was to determine the most relevant psychophysiological gender-specific differences in IBD. For this purpose, a questionnaire survey was conducted on disease activity and psychological concomitant diseases in patients with IBD (n = 300). Among the 218 patients with IBD who provided gender information, both genders were equally distributed. Results: Females with IBD are significantly more affected by IBD-related symptoms than men. Disease activity Scores Harvey-Bradshaw Index (HBI), Partial Mayo Score (pMAYO) showed no significant differences between the sexes in the subgroups with CD (HBI, m: 3 (IQR 1-6), w: 4 (IQR 2-8), p = 0.0677) and UC (pMAYO, m: 1 (IQR 0-4), w: 3 (IQR 0-5), p = 0.2118). IBD Questionnaire (IBDQ)shows significant differences in the gender-specific analysis. The mean value of the IBDQ total score of the female participants was 4.4 (SD 1.1) and that of men was 5.0 (SD 1.0) (p = 0.0002). Conclusions: There is a great need to investigate the causality of gender-specific differences in greater depth.
Beschreibung:Gesehen am 22.04.2025
Beschreibung:Online Resource
ISSN:2077-0383
DOI:10.3390/jcm13247806

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