PET/CT imaging of differentiated and medullary thyroid carcinoma using the novel SSTR-targeting peptide (18F)SiTATE: first clinical experiences

The novel 18F-labeled somatostatin receptor (SSTR)-directed radiotracer [18F]SiTATE demonstrated promising results for the imaging of various SSTR-expressing tumor types. Although thyroid carcinomas (TC) express SSTR, data on [18F]SiTATE PET/CT imaging in TC are lacking. This study explores the use...

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Main Authors: Kunte, Sophie Carina (Author) , Wenter, Vera (Author) , Toms, Johannes (Author) , Lindner, Simon (Author) , Unterrainer, Marcus (Author) , Eilsberger, Friederike (Author) , Jurkschat, Klaus (Author) , Wängler, Carmen (Author) , Wängler, Björn (Author) , Schirrmacher, Ralf (Author) , Tiling, Maximilian W. (Author) , Sheikh, Gabriel T. (Author) , Mehrens, Dirk (Author) , Brendel, Matthias (Author) , Rübenthaler, Johannes (Author) , Auernhammer, Christoph J. (Author) , Spitzweg, Christine (Author) , Unterrainer, Lena M. (Author) , Holzgreve, Adrien (Author)
Format: Article (Journal)
Language:English
Published: February 2025
In: European journal of nuclear medicine and molecular imaging
Year: 2025, Volume: 52, Issue: 3, Pages: 900-912
ISSN:1619-7089
DOI:10.1007/s00259-024-06944-y
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.1007/s00259-024-06944-y
Verlag, kostenfrei, Volltext: https://link.springer.com/article/10.1007/s00259-024-06944-y
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Author Notes:Sophie C. Kunte, Vera Wenter, Johannes Toms, Simon Lindner, Marcus Unterrainer, Friederike Eilsberger, Klaus Jurkschat, Carmen Wängler, Björn Wängler, Ralf Schirrmacher, Maximilian W. Tiling, Gabriel T. Sheikh, Dirk Mehrens, Matthias Brendel, Johannes Rübenthaler, Christoph J. Auernhammer, Christine Spitzweg, Lena M. Unterrainer, Adrien Holzgreve
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Summary:The novel 18F-labeled somatostatin receptor (SSTR)-directed radiotracer [18F]SiTATE demonstrated promising results for the imaging of various SSTR-expressing tumor types. Although thyroid carcinomas (TC) express SSTR, data on [18F]SiTATE PET/CT imaging in TC are lacking. This study explores the use of [18F]SiTATE PET/CT in a patient cohort with histologically proven TC.
Item Description:Im Titel ist 18 hochgestellt, (18F) steht dabei in eckigen Klammern
Online verfügbar: 15. Oktober 2024
Gesehen am 25.04.2025
Physical Description:Online Resource
ISSN:1619-7089
DOI:10.1007/s00259-024-06944-y