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Effects of cognitive training under hypoxia on cognitive proficiency and neuroplasticity in remitted patients with mood disorders and healthy individuals: ALTIBRAIN study protocol for a randomized controlled trial

Cognitive impairment is prevalent across neuropsychiatric disorders but there is a lack of treatment strategies with robust, enduring effects. Emerging evidence indicates that altitude-like hypoxia cognition training may induce long-lasting neuroplasticity and improve cognition. We will investigate...

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Main Authors: Woznica Miskowiak, Kamilla (Author) , Damgaard, Viktoria (Author) , Schandorff, Johanna Mariegaard (Author) , Macoveanu, Julian (Author) , Knudsen, Gitte Moos (Author) , Johansen, Annette (Author) , Plaven-Sigray, Pontus (Author) , Svarer, Claus (Author) , Fussing, Caroline Bruun (Author) , Cramer, Katrine (Author) , Jørgensen, Martin Balslev (Author) , Kessing, Lars Vedel (Author) , Ehrenreich, Hannelore (Author)
Format: Article (Journal)
Language:English
Published: 03 October 2024
In: Trials
Year: 2024, Volume: 25, Pages: 1-15
ISSN:1468-6694
DOI:10.1186/s13063-024-08463-5
Online Access:Resolving-System, kostenfrei, Volltext: https://doi.org/10.1186/s13063-024-08463-5
Verlag, kostenfrei, Volltext: https://trialsjournal.biomedcentral.com/articles/10.1186/s13063-024-08463-5
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Author Notes:Kamilla Woznica Miskowiak, Viktoria Damgaard, Johanna Mariegaard Schandorff, Julian Macoveanu, Gitte Moos Knudsen, Annette Johansen, Pontus Plaven-Sigray, Claus Svarer, Caroline Bruun Fussing, Katrine Cramer, Martin Balslev Jørgensen, Lars Vedel Kessing and Hannelore Ehrenreich
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Summary:Cognitive impairment is prevalent across neuropsychiatric disorders but there is a lack of treatment strategies with robust, enduring effects. Emerging evidence indicates that altitude-like hypoxia cognition training may induce long-lasting neuroplasticity and improve cognition. We will investigate whether repeated cognition training under normobaric hypoxia can improve cognitive functions in healthy individuals and patients with affective disorders and the neurobiological underpinnings of such effects.
Item Description:Gesehen am 29.04.2025
Physical Description:Online Resource
ISSN:1468-6694
DOI:10.1186/s13063-024-08463-5

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