Guidelines for the prophylaxis and treatment of peritoneal metastases from colorectal cancer: a GRADE-approach for evidence evaluation and recommendations

Colorectal peritoneal metastases (CPM) are common in colorectal cancer patients. This article aims to provide GRADE guidelines for the use of hyperthermic intraperitoneal chemotherapy (HIPEC) in two clinical situations: (1) To determine the value of adjuvant HIPEC for the prevention of CPM in high-r...

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Main Authors: Goéré, Diane (Author) , Kusamura, Shigeki (Author) , Lurvink, Robin J. (Author) , Cinquini, Michela (Author) , Piso, Pompiliu (Author) , Levine, Edward (Author) , Hubner, Martin (Author) , Cortés Guiral, Delia (Author) , Brandl, Andreas (Author) , Spinelli, Antonino (Author) , De Hingh, Ignace H. J. T. (Author) , Deraco, Marcello (Author)
Format: Article (Journal)
Language:English
Published: April 2025
In: Journal of surgical oncology
Year: 2025, Volume: 131, Issue: 5, Pages: 804-809
ISSN:1096-9098
DOI:10.1002/jso.27957
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.1002/jso.27957
Verlag, kostenfrei, Volltext: https://onlinelibrary.wiley.com/doi/abs/10.1002/jso.27957
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Author Notes:Diane Goéré, Shigeki Kusamura, Robin J. Lurvink, Michela Cinquini, Pompiliu Piso, Edward Levine, Martin Hubner, Delia Cortés Guiral, Andreas Brandl, Antonino Spinelli, Ignace H.J.T. De Hingh, Marcello Deraco
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Summary:Colorectal peritoneal metastases (CPM) are common in colorectal cancer patients. This article aims to provide GRADE guidelines for the use of hyperthermic intraperitoneal chemotherapy (HIPEC) in two clinical situations: (1) To determine the value of adjuvant HIPEC for the prevention of CPM in high-risk colorectal cancer patients; (2) to determine the impact on survival of cytoreductive surgery and HIPEC followed by adjuvant systemic chemotherapy as compared to systemic chemotherapy alone in patients with CPM.
Item Description:Online veröffentlicht: 25 October 2024
Gesehen am 02.05.2025
Physical Description:Online Resource
ISSN:1096-9098
DOI:10.1002/jso.27957