Central obesity may account for most of the colorectal cancer risk linked to obesity: evidence from the UK Biobank prospective cohort

General obesity commonly represented by body mass index (BMI) is an established risk factor for colorectal cancer (CRC). However, it is unclear to what extent this association is accounted for by central obesity. We aimed to evaluate the associations between BMI, waist-to-hip ratio (WHR), and waist...

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Main Authors: Safizadeh, Fatemeh (Author) , Mandić, Marko (Author) , Schöttker, Ben (Author) , Hoffmeister, Michael (Author) , Brenner, Hermann (Author)
Format: Article (Journal)
Language:English
Published: April 2025
In: International journal of obesity
Year: 2025, Volume: 49, Issue: 4, Pages: 619-626
ISSN:1476-5497
DOI:10.1038/s41366-024-01680-7
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.1038/s41366-024-01680-7
Verlag, kostenfrei, Volltext: https://www.nature.com/articles/s41366-024-01680-7
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Author Notes:Fatemeh Safizadeh, Marko Mandic, Ben Schöttker, Michael Hoffmeister and Hermann Brenner
Description
Summary:General obesity commonly represented by body mass index (BMI) is an established risk factor for colorectal cancer (CRC). However, it is unclear to what extent this association is accounted for by central obesity. We aimed to evaluate the associations between BMI, waist-to-hip ratio (WHR), and waist circumference (WC) with CRC risk and to investigate if and to what extent these associations are independent from each other.
Item Description:Online verfügbar: 19. November 2024
Gesehen am 14.05.2025
Physical Description:Online Resource
ISSN:1476-5497
DOI:10.1038/s41366-024-01680-7