Cover Image

The prognostic relevance of pleural effusion in patients with COVID-19: a German multicenter study : cardiothoracic imaging

Purpose - This study evaluates the prognostic significance of pleural effusion (PE) in COVID-19 patients across thirteen centers in Germany, aiming to clarify its role in predicting clinical outcomes. - Methods - In this retrospective analysis within the RACOON project (Radiological Cooperative Netw...

Full description

Saved in:
Bibliographic Details
Main Authors: Bucher, Andreas M. (Author) , Dietz, Julia (Author) , Ehrengut, Constantin (Author) , Müller, Lukas (Author) , Schramm, Dominik (Author) , Akinina, Alena (Author) , Drechsel, Michelle (Author) , Klöckner, Roman Trutz (Author) , Sieren, Malte Maria (Author) , Isfort, Peter (Author) , Sähn, Marwin-Jonathan (Author) , Fink, Matthias A. (Author) , Móré, Dorottya (Author) , Melekh, Bohdan (Author) , Meinel, Felix Gabriel (Author) , Schön, Hanna (Author) , May, Matthias (Author) , Siegler, Lisa (Author) , Münzfeld, Hanna (Author) , Ruppel, Richard (Author) , Penzkofer, Tobias (Author) , Kim, Moon Sung (Author) , Balzer, Miriam (Author) , Borggrefe, Jan (Author) , Meyer, Hans-Jonas (Author) , Surov, Alexey (Author)
Format: Article (Journal)
Language:English
Published: January 2025
In: Clinical imaging
Year: 2025, Volume: 117, Pages: 1-6
ISSN:1873-4499
DOI:10.1016/j.clinimag.2024.110303
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.1016/j.clinimag.2024.110303
Verlag, kostenfrei, Volltext: https://www.sciencedirect.com/science/article/pii/S089970712400233X
Get full text
Author Notes:Andreas Michael Bucher, Julia Dietz, Constantin Ehrengut, Lukas Müller, Dominik Schramm, Alena Akinina, Michelle Drechsel, Roman Kloeckner, Malte Sieren, Peter Isfort, Marwin-Jonathan Sähn, Matthias A. Fink, Dorottya Móré, Bohdan Melekh, Felix G. Meinel, Hanna Schön, Matthias Stefan May, Lisa Siegler, Hanna Münzfeld, Richard Ruppel, Tobias Penzkofer, Moon-Sung Kim, Miriam Balzer, Jan Borggrefe, Hans Jonas Meyer, Alexey Surov
Description
Summary:Purpose - This study evaluates the prognostic significance of pleural effusion (PE) in COVID-19 patients across thirteen centers in Germany, aiming to clarify its role in predicting clinical outcomes. - Methods - In this retrospective analysis within the RACOON project (Radiological Cooperative Network of the COVID-19 pandemic), 1183 patients (29.3 % women, 70.7 % men) underwent chest CT to assess PE. We investigated PE's association with 30-day mortality, ICU admission, and the need for mechanical ventilation. - Results - PE was detected in 31.5 % of patients, showing a significant correlation with 30-day mortality (47.5 % in non-survivors vs. 27.3 % in survivors, p < 0.001), with a hazard ratio of 2.22 (95 % CI 1.65-2.99, p < 0.001). No significant association was found between PE volume or density and mortality. ICU admissions were noted in 46.8 % of patients, while mechanical ventilation was required for 26.7 %. - Conclusion - Pleural effusion is present in a significant portion of COVID-19 patients and independently predicts increased 30-day mortality, underscoring its value as a prognostic marker. Its identification, irrespective of volume or density, should be a priority in radiological reports to guide clinical decision-making.
Item Description:Online verfügbar: 26. September 2024, Artikelversion: 11. November 2024
Gesehen am 27.05.2025
Physical Description:Online Resource
ISSN:1873-4499
DOI:10.1016/j.clinimag.2024.110303

Similar Items