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Pulmonary MRI in newborns and children

Lung MRI is an important tool in the assessment and monitoring of pediatric and neonatal lung disorders. MRI can provide both similar and complementary image contrast to computed tomography for imaging the lung macrostructure, and beyond this, a number of techniques have been developed for imaging t...

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Main Authors: Stewart, Neil J. (Author) , Higano, Nara S. (Author) , Wucherpfennig, Lena (Author) , Triphan, Simon M. F. (Author) , Simmons, Amy (Author) , Smith, Laurie J. (Author) , Wielpütz, Mark Oliver (Author) , Woods, Jason C. (Author) , Wild, Jim M. (Author)
Format: Article (Journal)
Language:English
Published: May 2025
In: Journal of magnetic resonance imaging
Year: 2025, Volume: 61, Issue: 5, Pages: 2094-2115
ISSN:1522-2586
DOI:10.1002/jmri.29669
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.1002/jmri.29669
Verlag, kostenfrei, Volltext: https://onlinelibrary.wiley.com/doi/abs/10.1002/jmri.29669
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Author Notes:Neil J. Stewart, PhD, Nara S. Higano, PhD, Lena Wucherpfennig, MD, Simon M.F. Triphan, PhD, Amy Simmons, MPhys, Laurie J. Smith, PhD, Mark O. Wielpütz, MD, Jason C. Woods, PhD, and Jim M. Wild, PhD
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Summary:Lung MRI is an important tool in the assessment and monitoring of pediatric and neonatal lung disorders. MRI can provide both similar and complementary image contrast to computed tomography for imaging the lung macrostructure, and beyond this, a number of techniques have been developed for imaging the key functions of the lungs, namely ventilation, perfusion, and gas exchange, through the use of free-breathing proton and hyperpolarized gas MRI. Here, we review the state-of-the-art in MRI methods that have found utility in pediatric and neonatal lung imaging, the structural and physiological information that can be gleaned from such images, and strategies that have been developed to deal with respiratory (and cardiac) motion, and other technological challenges. The application of lung MRI in neonatal and pediatric lung conditions, in particular bronchopulmonary dysplasia, cystic fibrosis, and asthma, is reviewed, highlighting our collective experiences in the clinical translation of these methods and technology, and the key current and future potential avenues for clinical utility of this methodology. Evidence Level 2 Technical Efficacy Stage 2
Item Description:Zuerst veröffentlicht: 06. Dezember 2024
Gesehen am 03.06.2025
Physical Description:Online Resource
ISSN:1522-2586
DOI:10.1002/jmri.29669

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