Targeting immune-checkpoint inhibitor resistance mechanisms by MEK inhibitor and agonist anti-CD40 antibody combination therapy
Targeting immune-checkpoint inhibitor resistance mechanisms by MEK inhibitor and agonist anti-CD40 antibody combination therapy - - IDENTIFYING SUITABLE CYTOSTATIC DRUGS FOR COMBINATORIAL IMMUNOTHERAPY The main dilemma in finding combinations of cytostatic and immunostimulatory drugs that act synerg...
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| Main Authors: | , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
October 2020
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| In: |
Cell stress
Year: 2020, Volume: 4, Issue: 10, Pages: 248-251 |
| ISSN: | 2523-0204 |
| DOI: | 10.15698/cst2020.10.233 |
| Online Access: | Verlag, kostenfrei, Volltext: https://doi.org/10.15698/cst2020.10.233 Verlag, kostenfrei, Volltext: https://www.cell-stress.com/researcharticles/2020a-baumann-cell-stress/ 
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| Author Notes: | Daniel Baumann and Rienk Offringa |
| Summary: | Targeting immune-checkpoint inhibitor resistance mechanisms by MEK inhibitor and agonist anti-CD40 antibody combination therapy - - IDENTIFYING SUITABLE CYTOSTATIC DRUGS FOR COMBINATORIAL IMMUNOTHERAPY The main dilemma in finding combinations of cytostatic and immunostimulatory drugs that act synergistically is as follows. On the one hand, the aim is to induce tumor cell death, not merely stasis, thereby feeding the immune system with tumor antigen. On the other hand, it is essential not to (...) |
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| Item Description: | Gesehen am 06.06.2025 |
| Physical Description: | Online Resource |
| ISSN: | 2523-0204 |
| DOI: | 10.15698/cst2020.10.233 |