Definition and predictors of early recurrence in neoadjuvantly treated esophageal and gastroesophageal adenocarcinoma: a dual-center retrospective cohort study
Early recurrence after esophagectomy is often used as a surrogate for aggressive tumor biology and treatment failure. However, there is no standardized definition of early recurrence, and predictors for early recurrence are unknown. Therefore, we aimed to define an evidence-based cutoff to discrimin...
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| Main Authors: | , , , , , , , , , , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
March 2025
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| In: |
Annals of surgical oncology
Year: 2025, Volume: 32, Issue: 3, Pages: 1617-1627 |
| ISSN: | 1534-4681 |
| DOI: | 10.1245/s10434-024-16403-5 |
| Online Access: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1245/s10434-024-16403-5 Verlag, lizenzpflichtig, Volltext: https://link.springer.com/article/10.1245/s10434-024-16403-5 |
| Author Notes: | Ingmar F. Rompen, MD, Adrian T. Billeter, MD, PhD, Nerma Crnovrsanin, MD, Leila Sisic, MD, Kerstin J. Neuschütz, MD, Julian Musa, MD, Martin Bolli, MD, Lana Fourie, MD, Marko Kraljevic, MD, Mohammed Al-Saeedi, MD, Henrik Nienhüser, MD, and Beat P. Müller-Stich, MD |
| Summary: | Early recurrence after esophagectomy is often used as a surrogate for aggressive tumor biology and treatment failure. However, there is no standardized definition of early recurrence, and predictors for early recurrence are unknown. Therefore, we aimed to define an evidence-based cutoff to discriminate early and late recurrence and assess the influence of neoadjuvant treatment modalities for patients with esophageal or gastroesophageal-junction adenocarcinoma (EAC). |
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| Item Description: | Online verfügbar: 05. November 2024 Gesehen am 12.06.2025 |
| Physical Description: | Online Resource |
| ISSN: | 1534-4681 |
| DOI: | 10.1245/s10434-024-16403-5 |