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Lost in translation: the lack of agreement between surgeons and scientists regarding biomaterials research and innovation for treating bone defects

With over 2 million grafts performed annually, bone ranks second only to blood in the frequency of transplants. This high demand is primarily driven by the persistent challenges posed by bone defects, particularly following trauma or surgical interventions such as tumour excision. The demand for eff...

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Main Authors: Laubach, Markus (Author) , Whyte, Stephen (Author) , Chan, Ho Fai (Author) , Frankenbach-Désor, Tina (Author) , Mayer-Wagner, Susanne (Author) , Hildebrand, Frank (Author) , Holzapfel, Boris M. (Author) , Kneser, Ulrich (Author) , Dulleck, Uwe (Author) , Hutmacher, Dietmar W. (Author)
Format: Article (Journal)
Language:English
Published: 2024
In: BMC medicine
Year: 2024, Volume: 22, Pages: [1]-16
ISSN:1741-7015
DOI:10.1186/s12916-024-03734-z
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.1186/s12916-024-03734-z
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Author Notes:Markus Laubach, Stephen Whyte, Ho Fai Chan, Tina Frankenbach-Désor, Susanne Mayer-Wagner, Frank Hildebrand, Boris M. Holzapfel, Ulrich Kneser, Uwe Dulleck and Dietmar W. Hutmacher
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Summary:With over 2 million grafts performed annually, bone ranks second only to blood in the frequency of transplants. This high demand is primarily driven by the persistent challenges posed by bone defects, particularly following trauma or surgical interventions such as tumour excision. The demand for effective and efficient treatments has increased exponentially in the twenty-first century. Limitations associated with autologous bone grafts drive exploration into replacements, including allografts, synthetic substitutes, and 3D-printed scaffolds. This research aimed to unravel disparities in the knowledge and evaluation of current and future bone defect treatments between surgeons and biomaterial scientists.
Item Description:Online veröffentlicht: 6. November 2024
Gesehen am 28.07.2025
Physical Description:Online Resource
ISSN:1741-7015
DOI:10.1186/s12916-024-03734-z

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