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A system for stereotactic irradiation and magnetic resonance evaluations in the rat brain

Purpose: A stereoactic fixation and localization device developed for small animal stereotactic radiosurgery is described. Methods and Materials: Irradiated volumes of spherical shape down to 1.7 mm in diameter at the 80% isodose level are attainable. The fixation device can also be used for magneti...

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Bibliographische Detailangaben
Hauptverfasser: Karger, Christian (VerfasserIn) , Hartmann, Günther H. (VerfasserIn) , Hoffmann, Ulf (VerfasserIn) , Lorenz, Walter Josef (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 30 September 1995
In: International journal of radiation oncology, biology, physics
Year: 1995, Jahrgang: 33, Heft: 2, Pages: 485-492
ISSN:1879-355X
DOI:10.1016/0360-3016(95)00066-8
Online-Zugang:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1016/0360-3016(95)00066-8
Verlag, lizenzpflichtig, Volltext: https://www.sciencedirect.com/science/article/pii/0360301695000668
Volltext
Verfasserangaben:Christian P. Karger, Günther H. Hartmann, Ulf Hoffmann, Walter J. Lorenz
Beschreibung
Zusammenfassung:Purpose: A stereoactic fixation and localization device developed for small animal stereotactic radiosurgery is described. Methods and Materials: Irradiated volumes of spherical shape down to 1.7 mm in diameter at the 80% isodose level are attainable. The fixation device can also be used for magnetic resonance imaging (MRI) and allows target localization during magneitc resonance (MR) image content measurement. The capabilities of the entire system were investigated using a phantom that permitted measurement and localization of the three-dimensional dose distribution. Localization of target isocenter coordinates in MR images was also checked with the phantom. Results: An overall spatial error of about 1 mm for subsequent stereotactic irradiation was obtained. Conclusions: The accuracy of the fixation and localization techniques is adequate to investigate radiation-induced changes in the rat brain.
Beschreibung:Elektronische Reproduktion der Druck-Ausgabe 23. Februar 2000
Gesehen am 29.07.2025
Beschreibung:Online Resource
ISSN:1879-355X
DOI:10.1016/0360-3016(95)00066-8

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