Influence of field strength on quantitative parameters and feature stability in the assessment of the ovaries using 1.5-T and 3-T MRI
Background - Little is known of the influence of scanner field strength on quantitative diffusivity variables, especially kurtosis in healthy ovaries. - Purpose - To evaluate the influence of scanner field strength on quantitative diffusion variables in pelvic MRI of the ovaries. - Material and Meth...
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| Main Authors: | , , , , , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
May 2025
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| In: |
Acta radiologica
Year: 2025, Volume: 66, Issue: 5, Pages: 512-520 |
| ISSN: | 1600-0455 |
| DOI: | 10.1177/02841851241313021 |
| Online Access: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1177/02841851241313021
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| Author Notes: | Theresa Mokry, Judith Pantke, Hans-Ulrich Kauczor, Frederik B Laun, Heinz-Peter Schlemmer, Tristan A Kuder, Sebastian Bickelhaupt |
| Summary: | Background - Little is known of the influence of scanner field strength on quantitative diffusivity variables, especially kurtosis in healthy ovaries. - Purpose - To evaluate the influence of scanner field strength on quantitative diffusion variables in pelvic MRI of the ovaries. - Material and Methods - This prospective, single-centre study consisted of repeated 1.5-T and 3-T examinations in 30 female volunteers (mean age=27.9 years, age range=20.3-45.2 years) from July 2017 to September 2019. Multi b-value DWI 0, 50, 100, 800, 1500, 2000 s/mm2 was acquired over three timepoints during the menstrual cycle. Ovaries were segmented at b = 1500 s/mm2. Median apparent diffusion coefficient (ADC) and advanced kurtosis parameters Dapp and Kapp were calculated. Statistical analysis was performed with the variations of diffusivity variables being compared between 1.5-T and 3-T MRI using a Mann-Whitney rank-sum test. - Results - Median ADC and Dapp (µm²/ms) did not statistically differ. Median ADC were 1.509 (range=1.371-1.610), 1.619 (range=1.463-1.747), and 1.511 (range=1.423-1.639) at 1.5 T; 1.542 (range=1.428-1.682), 1.658 (range=1.510-1.806), and 1.572 (range=1.455-1.709) at 3 T (P = 0.14, 0.19, and 0.07), whereas median Dapp were 2.024 (range=1.913-2.152), 2.192 (range=2.010-2.327), and 2.045 (range=1.958-2.170) at 1.5 T; 2.013 (range=1.952-2.188), 2.179 (range=2.018-2.327), and 2.082 (range=1.959-2.194) at 3 T (P = 0.77, 0.99, and 0.34) for timepoints 1, 2, and 3, respectively. Statistical comparison of Kapp revealed significant differences for all timepoints: 0.629 (range=0.595-0.652), 0.604 (range=0.574-0.651), and 0.622 (range=0.581-0.664) at 1.5 T; 0.601 (range=0.563-0.626), 0.567 (range=0.526-0.633), and 0.599 (range=0.541-0.650) at 3 T (P < 0.001, 0.005, and 0.03). - Conclusion - Diffusivity mapping in the ovaries provides similar absolute median diffusion values, but statistically significant differences in absolute kurtosis values between 1.5 T and 3 T. |
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| Item Description: | Online veröffentlicht: 4. Februar 2025 Gesehen am 30.07.2025 |
| Physical Description: | Online Resource |
| ISSN: | 1600-0455 |
| DOI: | 10.1177/02841851241313021 |