Buchumschlag

Dual antiplatelet pre-treatment with aspirin and ticagrelor in ACS patients undergoing unplanned aortocoronary bypass surgery

Major bleedings following coronary artery bypass grafting (CABG) have significant implications on outcomes in acute coronary syndrome (ACS) patients. Owing fears of fatal bleedings in case of urgent CABG, current guidelines recommend a cessation of P2Y12 receptor antagonists (P2Y12-RA) before cardia...

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Bibliographische Detailangaben
Hauptverfasser: Salbach, Christian (VerfasserIn) , Yildirim, Mustafa (VerfasserIn) , Gulba, Rebecca (VerfasserIn) , Milles, Barbara Ruth (VerfasserIn) , Biener, Moritz (VerfasserIn) , Müller-Hennessen, Matthias (VerfasserIn) , Hund, Hauke (VerfasserIn) , Frey, Norbert (VerfasserIn) , Giannitsis, Evangelos (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: June 2025
In: Clinical research in cardiology
Year: 2025, Jahrgang: 114, Heft: 6, Pages: 772-782
ISSN:1861-0692
DOI:10.1007/s00392-025-02629-0
Online-Zugang:Verlag, kostenfrei, Volltext: https://doi.org/10.1007/s00392-025-02629-0
Verlag, kostenfrei, Volltext: https://link.springer.com/article/10.1007/s00392-025-02629-0
Volltext
Verfasserangaben:Christian Salbach, Mustafa Yildirim, Rebecca Gulba, Barbara Ruth Milles, Moritz Biener, Matthias Mueller-Hennessen, Hauke Hund, Norbert Frey, Evangelos Giannitsis
Beschreibung
Zusammenfassung:Major bleedings following coronary artery bypass grafting (CABG) have significant implications on outcomes in acute coronary syndrome (ACS) patients. Owing fears of fatal bleedings in case of urgent CABG, current guidelines recommend a cessation of P2Y12 receptor antagonists (P2Y12-RA) before cardiac surgery and opt against routine pre-treatment with a P2Y12-RA before coronary angiography (CA). However, sparse information exists outside randomized trials on the frequency of urgent CABG and the consequences of inappropriately long cessation of P2Y12-RA treatment in patients presenting with ACS.
Beschreibung:Online verfügbar: 12. März 2025
Gesehen am 08.08.2025
Beschreibung:Online Resource
ISSN:1861-0692
DOI:10.1007/s00392-025-02629-0

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