Effect of medically lowering intraocular pressure in glaucoma suspects with high myopia (GSHM study): study protocol for a randomized controlled trial

Currently, whether and when intraocular pressure (IOP)-lowering medication should be used in glaucoma suspects with high myopia (GSHM) remains unknown. Glaucoma suspects are visual field (VF) defects that cannot be explained by myopic macular changes or other retinal and neurologic conditions. Glauc...

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Main Authors: Lin, Fengbin (Author) , Da Chen, Shi (Author) , Song, Yun He (Author) , Wang, Wei (Author) , Jin, Ling (Author) , Liu, Bing Qian (Author) , Liu, Yu Hong (Author) , Chen, Mei Ling (Author) , Gao, Kai (Author) , Friedman, David S. (Author) , Jonas, Jost B. (Author) , Aung, Tin (Author) , Lv, Lin (Author) , Liu, Yi Zhi (Author) , Zhang, Xiu Lan (Author)
Format: Article (Journal)
Language:English
Published: 29 September 2020
In: Trials
Year: 2020, Volume: 21, Pages: 1-12
ISSN:1468-6694
DOI:10.1186/s13063-020-04748-7
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.1186/s13063-020-04748-7
Verlag, kostenfrei, Volltext: https://trialsjournal.biomedcentral.com/articles/10.1186/s13063-020-04748-7
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Author Notes:Feng Bin Lin, Shi Da Chen, Yun He Song, Wei Wang, Ling Jin, Bing Qian Liu, Yu Hong Liu, Mei Ling Chen, Kai Gao, David S. Friedman, Jost B. Jonas, Tin Aung, Lin Lv, Yi Zhi Liu, Xiu Lan Zhang on behalf of the GSHM study group
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Summary:Currently, whether and when intraocular pressure (IOP)-lowering medication should be used in glaucoma suspects with high myopia (GSHM) remains unknown. Glaucoma suspects are visual field (VF) defects that cannot be explained by myopic macular changes or other retinal and neurologic conditions. Glaucoma progression is defined by VF deterioration. Here we describe the rationale, design, and methodology of a randomized controlled trial (RCT) designed to evaluate the effects of medically lowering IOP in GSHM (GSHM study).
Item Description:Gesehen am 11.08.2025
Physical Description:Online Resource
ISSN:1468-6694
DOI:10.1186/s13063-020-04748-7