Epineural scarring visualization and noninvasive quantification of a severe posttraumatic complication: an experimental magnetic resonance neurography Study

Peripheral nerve scarring is a severe yet common complication following nerve injury or surgery that can lead to impaired nerve function, including chronic pain and sensory or motor deficits. In this study, we aimed to establish high-resolution magnetic resonance neurography (MRN) to accurately visu...

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Main Authors: Brunnée, Merle (Author) , Aman, Martin (Author) , Mayrhofer-Schmid, Maximilian (Author) , Fischer, Manuel (Author) , Däschler, Simeon C. (Author) , Klemm, Tess (Author) , Kneser, Ulrich (Author) , Karimian-Jazi, Kianush (Author) , Breckwoldt, Michael O. (Author) , Harhaus-Wähner, Leila (Author) , Heiland, Sabine (Author) , Bendszus, Martin (Author) , Böcker, Arne Hendrik (Author) , Schwarz, Daniel (Author)
Format: Article (Journal)
Language:English
Published: April 2025
In: Investigative radiology
Year: 2025, Volume: 60, Issue: 4, Pages: 275-280
ISSN:1536-0210
DOI:10.1097/RLI.0000000000001132
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1097/RLI.0000000000001132
Verlag, lizenzpflichtig, Volltext: https://journals.lww.com/investigativeradiology/abstract/2025/04000/epineural_scarring_visualization_and_noninvasive.5.aspx
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Author Notes:Brunnée, Merle, MD, Aman, Martin, MD, PhD, Mayrhofer-Schmid, Maximilian, Fischer, Manuel, Daeschler, Simeon C., MD, Klemm, Tess, Kneser, Ulrich, MD, Karimian-Jazi, Kianush, MD, Breckwoldt, Michael O., MD, Harhaus, Leila, MD, Heiland, Sabine, PhD, Bendszus, Martin, MD, Boecker, Arne H., MD, Schwarz, Daniel, MD
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Summary:Peripheral nerve scarring is a severe yet common complication following nerve injury or surgery that can lead to impaired nerve function, including chronic pain and sensory or motor deficits. In this study, we aimed to establish high-resolution magnetic resonance neurography (MRN) to accurately visualize and monitor de novo–formed epineural fibrotic adhesions (EFAs) of the sciatic nerve in a rat nerve injury model.
Item Description:Gesehen am 11.08.2025
Physical Description:Online Resource
ISSN:1536-0210
DOI:10.1097/RLI.0000000000001132