A facility for laboratory mice with a natural microbiome at Charité - Universitätsmedizin Berlin
Mice with a natural microbiome are a promising research model for basic and applied science because of their closer resemblance to the human superorganism compared to mice born and raised under stringent hygiene conditions. Consequently, biomedical therapies developed and tested in “Wildling mice” h...
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| Main Authors: | , , , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
2024
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| In: |
Lab animal
Year: 2024, Volume: 53, Issue: 12, Pages: 351-354 |
| ISSN: | 1548-4475 |
| DOI: | 10.1038/s41684-024-01474-4 |
| Online Access: | Verlag, kostenfrei, Volltext: https://doi.org/10.1038/s41684-024-01474-4 Verlag, kostenfrei, Volltext: https://www.nature.com/articles/s41684-024-01474-4 
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| Author Notes: | Natascha Drude, Stefan Nagel-Riedasch, Stephan P. Rosshart, Andreas Diefenbach (The "Charité 3R Wildling Mouse Model in Health and Disease (C3R Wildling HeaD)" Consortium) & Stefan Jordan |
| Summary: | Mice with a natural microbiome are a promising research model for basic and applied science because of their closer resemblance to the human superorganism compared to mice born and raised under stringent hygiene conditions. Consequently, biomedical therapies developed and tested in “Wildling mice” hold great potential for successful translation into clinical applications. Over the past four years, scientists, veterinarians and institutional officials at Charité - Universitätsmedizin Berlin, supported by the University Hospital Erlangen, have designed a facility for Wildling mice and developed a conceptual framework for safe and ethical preclinical research involving mice with a natural microbiome. |
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| Item Description: | Online veröffentlicht: 12. November 2024 Gesehen am 13.08.2025 |
| Physical Description: | Online Resource |
| ISSN: | 1548-4475 |
| DOI: | 10.1038/s41684-024-01474-4 |