Identification of patients with suspected NSTE-ACS in the observe zone: evaluating GRACE 1.0 score and a biomarker panel for risk stratification and management optimization

Current guidelines recommend additional diagnostic work-up for patients with suspected non-ST-elevation acute coronary syndrome (NSTE-ACS) triaged in the observe zone using accelerated diagnostic protocols. This study assessed the effectiveness of combining the Global Registry of Acute Coronary Even...

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Main Authors: Yildirim, Mustafa (Author) , Reich, Christoph (Author) , Salbach, Christian (Author) , Biener, Moritz (Author) , Müller-Hennessen, Matthias (Author) , Sörensen, Nils Arne (Author) , Haller, Paul Michael (Author) , Blankenberg, Stefan (Author) , Neumann, Johannes Tobias (Author) , Twerenbold, Raphael (Author) , Frey, Norbert (Author) , Giannitsis, Evangelos (Author)
Format: Article (Journal)
Language:English
Published: 14 April 2025
In: Clinical research in cardiology
Year: 2025, Volume: 114, Issue: 6, Pages: 783-795
ISSN:1861-0692
DOI:10.1007/s00392-025-02642-3
Online Access:Resolving-System, kostenfrei, Volltext: https://doi.org/10.1007/s00392-025-02642-3
Verlag, kostenfrei, Volltext: https://link.springer.com/article/10.1007/s00392-025-02642-3
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Author Notes:Mustafa Yildirim, Christoph Reich, Christian Salbach, Moritz Biener, Matthias Mueller-Hennessen, Nils Arne Sörensen, Paul Michael Haller, Stefan Blankenberg, Johannes Tobias Neumann, Raphael Twerenbold, Norbert Frey, Evangelos Giannitsis
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Summary:Current guidelines recommend additional diagnostic work-up for patients with suspected non-ST-elevation acute coronary syndrome (NSTE-ACS) triaged in the observe zone using accelerated diagnostic protocols. This study assessed the effectiveness of combining the Global Registry of Acute Coronary Events (GRACE) 1.0 score with additional non-cardio-specific biomarkers for risk stratification in the observe zone.
Item Description:Gesehen am 28.08.2025
Physical Description:Online Resource
ISSN:1861-0692
DOI:10.1007/s00392-025-02642-3