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Update Breast Cancer 2024 part 2 - patients with early stage breast cancer

This review summarizes the latest developments for the treatment of patients with early-stage breast cancer. Most of the clinically relevant changes were the result of using immune checkpoint inhibitors to treat patients with triple-negative breast cancer (TNBC) and CDK4/6 inhibitors to treat patien...

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Main Authors: Janni, Wolfgang (Author) , Kolberg, Hans-Christian (Author) , Hartkopf, Andreas (Author) , Fehm, Tanja (Author) , Welslau, Manfred (Author) , Müller, Volkmar (Author) , Schütz, Florian (Author) , Fasching, Peter Andreas (Author) , Jackisch, Christian (Author) , Marmé, Frederik (Author) , Hörner, Manuel (Author) , Keller, Katharina (Author) , Goossens, Chloë (Author) , Belleville, Erik (Author) , Untch, Michael (Author) , Thill, Marc (Author) , Tesch, Hans (Author) , Ditsch, Nina (Author) , Lux, Michael P. (Author) , BanysPaluchowski, Maggie (Author) , Wöckel, Achim (Author) , Harbeck, Nadia (Author) , Stickeler, Elmar (Author) , Bartsch, Rupert (Author) , Aktas, Bahriye (Author) , Schneeweiss, Andreas (Author) , Ettl, Johannes (Author) , Ţăran, FlorinAndrei (Author) , Lüftner, Diana (Author) , Würstlein, Rachel (Author) , Radosa, Julia (Author)
Format: Article (Journal)
Language:English
Published: Mai 2025
In: Geburtshilfe und Frauenheilkunde
Year: 2025, Volume: 85, Issue: 05, Pages: 493506
ISSN:14388804
DOI:10.1055/a-2533-2783
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.1055/a-2533-2783
Verlag, kostenfrei, Volltext: http://www.thieme-connect.de/DOI/DOI?10.1055/a-2533-2783
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Author Notes:Authors: Wolfgang Janni, Hans-Christian Kolberg, Andreas D. Hartkopf, Tanja N. Fehm, Manfred Welslau, Volkmar Müller, Florian Schütz, Peter A. Fasching, Christian Jackisch, Frederik Marme, Manuel Hörner, Katharina Keller, Chloë Goossens, Erik Belleville, Michael Untch, Marc Thill, Hans Tesch, Nina Ditsch, Michael P. Lux, Maggie Banys-Paluchowski, Achim Wöckel, Nadia Harbeck, Elmar Stickeler, Rupert Bartsch, Bahriye Aktas, Andreas Schneeweiss, Johannes Ettl, Florin-Andrei Taran, Diana Lüftner, Rachel Würstlein, Julia C. Radosa
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Summary:This review summarizes the latest developments for the treatment of patients with early-stage breast cancer. Most of the clinically relevant changes were the result of using immune checkpoint inhibitors to treat patients with triple-negative breast cancer (TNBC) and CDK4/6 inhibitors to treat patients with hormone receptor-positive, HER2-negative (HRpos/HER2neg) tumors and a high risk of recurrence. Recent studies are presenting more and more data with long follow-up times and integrating translational analyses to evaluate new biomarkers such as circulating tumor DNA (ctDNA). This review article summarizes the latest developments published in recent months and puts the findings in context.
Item Description:Online veröffentlicht: 15. Mai 2025
Gesehen am 01.09.2025
Physical Description:Online Resource
ISSN:14388804
DOI:10.1055/a-2533-2783

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