Intradermal advanced glycation end-products relate to reduced sciatic nerve structural integrity in type 2 diabetes
Cardiovascular risk management is beneficial, but stringent glycemic control does not prevent the progression of distal sensorimotor polyneuropathy (DSPN). Persistent hyperglycemia-induced alterations and cardiovascular factors may contribute to diabetes-associated nerve damage. This study aimed to...
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| Hauptverfasser: | , , , , , , , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
29 January 2025
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| In: |
Clinical neuroradiology
Year: 2025, Jahrgang: 35, Heft: 2, Pages: 385-394 |
| ISSN: | 1869-1447 |
| DOI: | 10.1007/s00062-024-01493-1 |
| Online-Zugang: | Verlag, kostenfrei, Volltext: https://doi.org/10.1007/s00062-024-01493-1 |
| Verfasserangaben: | Christoph M. Mooshage, Dimitrios Tsilingiris, Lukas Schimpfle, Thomas Fleming, Stephan Herzig, Julia Szendroedi, Sabine Heiland, Martin Bendszus, Stefan Kopf, Felix Kurz, Johann Jende, Zoltan Kender |
| Zusammenfassung: | Cardiovascular risk management is beneficial, but stringent glycemic control does not prevent the progression of distal sensorimotor polyneuropathy (DSPN). Persistent hyperglycemia-induced alterations and cardiovascular factors may contribute to diabetes-associated nerve damage. This study aimed to evaluate the correlation between skin auto-fluorescence (sAF), an indicator of dermal advanced glycation end-product (AGE) accumulations, cardiovascular risk, and changes in peripheral nerve integrity. |
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| Beschreibung: | Gesehen am 17.09.2025 |
| Beschreibung: | Online Resource |
| ISSN: | 1869-1447 |
| DOI: | 10.1007/s00062-024-01493-1 |