Response to neoadjuvant treatment among rectal cancer patients in a population-based cohort

In rectal cancer, prediction of tumor response and pathological complete response (pCR) to neoadjuvant treatment could contribute to refine selection of patients who might benefit from a delayed- or no-surgery approach. The aim of this study was to explore the association of clinical and molecular c...

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Main Authors: Alwers, Elizabeth (Author) , Jansen, Lina (Author) , Kather, Jakob Nikolas (Author) , Amitay, Efrat L. (Author) , Bläker, Hendrik (Author) , Kloor, Matthias (Author) , Tagscherer, Katrin (Author) , Roth, Wilfried (Author) , Herpel, Esther (Author) , Chang-Claude, Jenny (Author) , Brenner, Hermann (Author) , Hoffmeister, Michael (Author)
Format: Article (Journal)
Language:English
Published: January 2021
In: International journal of colorectal disease
Year: 2021, Volume: 36, Issue: 1, Pages: 177-185
ISSN:1432-1262
DOI:10.1007/s00384-020-03744-2
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.1007/s00384-020-03744-2
Verlag, kostenfrei, Volltext: https://link.springer.com/article/10.1007/s00384-020-03744-2
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Author Notes:Elizabeth Alwers, Lina Jansen, Jakob Kather, Efrat Amitay, Hendrik Bläker, Matthias Kloor, Katrin E. Tagscherer, Wilfried Roth, Esther Herpel, Jenny Chang-Claude, Hermann Brenner, Michael Hoffmeister
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Summary:In rectal cancer, prediction of tumor response and pathological complete response (pCR) to neoadjuvant treatment could contribute to refine selection of patients who might benefit from a delayed- or no-surgery approach. The aim of this study was to explore the association of clinical and molecular characteristics of rectal cancer with response to neoadjuvant treatment and to compare patient survival according to level of response.
Item Description:Online publiziert: 19. September 2020
Gesehen am 17.09.2025
Physical Description:Online Resource
ISSN:1432-1262
DOI:10.1007/s00384-020-03744-2