Response to neoadjuvant treatment among rectal cancer patients in a population-based cohort

In rectal cancer, prediction of tumor response and pathological complete response (pCR) to neoadjuvant treatment could contribute to refine selection of patients who might benefit from a delayed- or no-surgery approach. The aim of this study was to explore the association of clinical and molecular c...

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Hauptverfasser: Alwers, Elizabeth (VerfasserIn) , Jansen, Lina (VerfasserIn) , Kather, Jakob Nikolas (VerfasserIn) , Amitay, Efrat L. (VerfasserIn) , Bläker, Hendrik (VerfasserIn) , Kloor, Matthias (VerfasserIn) , Tagscherer, Katrin (VerfasserIn) , Roth, Wilfried (VerfasserIn) , Herpel, Esther (VerfasserIn) , Chang-Claude, Jenny (VerfasserIn) , Brenner, Hermann (VerfasserIn) , Hoffmeister, Michael (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: January 2021
In: International journal of colorectal disease
Year: 2021, Jahrgang: 36, Heft: 1, Pages: 177-185
ISSN:1432-1262
DOI:10.1007/s00384-020-03744-2
Online-Zugang:Verlag, kostenfrei, Volltext: https://doi.org/10.1007/s00384-020-03744-2
Verlag, kostenfrei, Volltext: https://link.springer.com/article/10.1007/s00384-020-03744-2
Volltext
Verfasserangaben:Elizabeth Alwers, Lina Jansen, Jakob Kather, Efrat Amitay, Hendrik Bläker, Matthias Kloor, Katrin E. Tagscherer, Wilfried Roth, Esther Herpel, Jenny Chang-Claude, Hermann Brenner, Michael Hoffmeister
Beschreibung
Zusammenfassung:In rectal cancer, prediction of tumor response and pathological complete response (pCR) to neoadjuvant treatment could contribute to refine selection of patients who might benefit from a delayed- or no-surgery approach. The aim of this study was to explore the association of clinical and molecular characteristics of rectal cancer with response to neoadjuvant treatment and to compare patient survival according to level of response.
Beschreibung:Online publiziert: 19. September 2020
Gesehen am 17.09.2025
Beschreibung:Online Resource
ISSN:1432-1262
DOI:10.1007/s00384-020-03744-2