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Kidney transplantation in children and adolescents with C3 glomerulopathy or immune complex membranoproliferative glomerulonephritis: a real-world study within the CERTAIN research network

Complement 3 glomerulopathy (C3G) and immune complex membranoproliferative glomerulonephritis (IC-MPGN) are ultra-rare chronic kidney diseases with an overall poor prognosis, with approximately 40-50% of patients progressing to kidney failure within 10 years of diagnosis. C3G is characterized by a h...

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Main Authors: Patry, Christian (Author) , Webb, Nicholas J. A. (Author) , Feißt, Manuel (Author) , Krupka, Kai (Author) , Becker, Jan (Author) , Bald, Martin (Author) , Antoniello, Benedetta (Author) , Bilge, Ilmay (Author) , Gulhan, Bora (Author) , Hogan, Julien (Author) , Kanzelmeyer, Nele (Author) , Ozkaya, Ozan (Author) , Büscher, Anja (Author) , Sellier-Leclerc, Anne-Laure (Author) , Shenoy, Mohan (Author) , Weber, Lutz T. (Author) , Fichtner, Alexander (Author) , Höcker, Britta (Author) , Meier, Matthias (Author) , Tönshoff, Burkhard (Author)
Format: Article (Journal)
Language:English
Published: December 2024
In: Pediatric nephrology
Year: 2024, Volume: 39, Issue: 12, Pages: 3569-3580
ISSN:1432-198X
DOI:10.1007/s00467-024-06476-5
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.1007/s00467-024-06476-5
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Author Notes:Christian Patry, Nicholas J. A. Webb, Manuel Feißt, Kai Krupka, Jan Becker, Martin Bald, Benedetta Antoniello, Ilmay Bilge, Bora Gulhan, Julien Hogan, Nele Kanzelmeyer, Ozan Ozkaya, Anja Büscher, Anne-Laure Sellier-Leclerc, Mohan Shenoy, Lutz T. Weber, Alexander Fichtner, Britta Höcker, Matthias Meier, Burkhard Tönshoff
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Summary:Complement 3 glomerulopathy (C3G) and immune complex membranoproliferative glomerulonephritis (IC-MPGN) are ultra-rare chronic kidney diseases with an overall poor prognosis, with approximately 40-50% of patients progressing to kidney failure within 10 years of diagnosis. C3G is characterized by a high rate of disease recurrence in the transplanted kidney. However, there is a lack of published data on clinical outcomes in the pediatric population following transplantation.
Item Description:Online veröffentlicht: 7. August 2024
Gesehen am 29.09.2025
Physical Description:Online Resource
ISSN:1432-198X
DOI:10.1007/s00467-024-06476-5

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