Density and entropy of immune cells within the tumor microenvironment of primary tumors and matched brain metastases
Tumor-infiltrating lymphocytes (TILs) and tumor-associated macrophages (TAMs) have increasingly been reported to impact the brain metastatic process of solid tumors. However, data on intra-individual differences between primary tumor and brain metastasis (BM), as well as their correlation with clini...
Saved in:
| Main Authors: | , , , , , , , , , , , , , , |
|---|---|
| Format: | Article (Journal) |
| Language: | English |
| Published: |
Februar 2025
|
| In: |
Acta Neuropathologica Communications
Year: 2025, Volume: 13, Issue: 1, Pages: 1-12 |
| ISSN: | 2051-5960 |
| DOI: | 10.1186/s40478-025-01939-8 |
| Online Access: | Verlag, kostenfrei, Volltext: https://doi.org/10.1186/s40478-025-01939-8 |
| Author Notes: | Markus Kleinberger, Didem Çifçi, Christina Paiato, Erwin Tomasich, Maximilian J. Mair, Ariane Steindl, Zoltán Spiró, Zunamys I. Carrero, Luzia Berchtold, Johannes Hainfellner, Leonhard Müllauer, Gerwin Heller, Matthias Preusser, Jakob Niklas Kather and Anna Sophie Berghoff |
| Summary: | Tumor-infiltrating lymphocytes (TILs) and tumor-associated macrophages (TAMs) have increasingly been reported to impact the brain metastatic process of solid tumors. However, data on intra-individual differences between primary tumor and brain metastasis (BM), as well as their correlation with clinical outcome parameters, is scarce. |
|---|---|
| Item Description: | Online veröffentlicht am 19. Februar 2025 Gesehen am 13.10.2025 |
| Physical Description: | Online Resource |
| ISSN: | 2051-5960 |
| DOI: | 10.1186/s40478-025-01939-8 |