High fat diet induces gastric production of fibroblast growth factor 23 (FGF23)
A high fat diet (HFD) leads to lesions of the gastric epithelium and causes a proinflammatory environment. Fibroblast growth factor 23 (FGF23), a bone hormone, regulates renal phosphate and vitamin D metabolism. Under pathophysiological conditions production of FGF23 is stimulated. HFD feeding eleva...
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| Hauptverfasser: | , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
07 June 2025
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| In: |
International journal of obesity
Year: 2025, Jahrgang: 49, Heft: 9, Pages: 1733-1744 |
| ISSN: | 1476-5497 |
| DOI: | 10.1038/s41366-025-01808-3 |
| Online-Zugang: | Verlag, kostenfrei, Volltext: https://doi.org/10.1038/s41366-025-01808-3 Verlag, kostenfrei, Volltext: https://www.nature.com/articles/s41366-025-01808-3 |
| Verfasserangaben: | Patricia Widmayer, Martina Feger, Leonie Meier, Andreas H. Wagner and Michael Föller |
| Zusammenfassung: | A high fat diet (HFD) leads to lesions of the gastric epithelium and causes a proinflammatory environment. Fibroblast growth factor 23 (FGF23), a bone hormone, regulates renal phosphate and vitamin D metabolism. Under pathophysiological conditions production of FGF23 is stimulated. HFD feeding elevates serum FGF23 levels through inflammation. |
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| Beschreibung: | Gesehen am 21.10.2025 |
| Beschreibung: | Online Resource |
| ISSN: | 1476-5497 |
| DOI: | 10.1038/s41366-025-01808-3 |