Survival of anterior cruciate ligament  reconstruction in patients with Ehlers-Danlos syndrome: a comparison with anatomic risk factors in existing literature

Ehlers-Danlos Syndrome (EDS) is a connective tissue disorder characterized by joint hypermobility, ligamentous laxity, and frequent joint injuries. These features could increase the risk of anterior cruciate ligament (ACL) tears, typically managed through ACL reconstruction (ACLR). Surgical interven...

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Main Authors: Schmidt, Sebastian (Author) , Leite, Chilan Bou Ghosson (Author) , Bumberger, Alexander (Author) , Franco, Domenico (Author) , Jacobs, Cale Andrew (Author) , Richardson, Lars (Author) , Paschos, Nikolaos (Author) , Goertz, Simon (Author) , Berkson, Eric (Author) , Asnis, Peter (Author) , Lattermann, Christian (Author)
Format: Article (Journal)
Language:English
Published: October 2025
In: International orthopaedics
Year: 2025, Volume: 49, Issue: 10, Pages: 2433-2442
ISSN:1432-5195
DOI:10.1007/s00264-025-06632-y
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.1007/s00264-025-06632-y
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Author Notes:Sebastian Schmidt, Chilan Bou Ghosson Leite, Alexander Bumberger, Domenico Franco, Cale Andrew Jacobs, Lars Richardson, Nikolaos Paschos, Simon Goertz, Eric Berkson, Peter Asnis, Christian Lattermann
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Summary:Ehlers-Danlos Syndrome (EDS) is a connective tissue disorder characterized by joint hypermobility, ligamentous laxity, and frequent joint injuries. These features could increase the risk of anterior cruciate ligament (ACL) tears, typically managed through ACL reconstruction (ACLR). Surgical intervention in EDS is challenging due to potential complications such as poor wound healing and tissue fragility. Limited evidence exists regarding the outcomes of ACLR in EDS patients; therefore, in this study we aimed to evaluate survival rates of primary and revision ACLR and examine associated demographic and anatomic risk factors for failure after ACLR.
Item Description:Online veröffentlicht: 7. August 2025
Gesehen am 30.10.2025
Physical Description:Online Resource
ISSN:1432-5195
DOI:10.1007/s00264-025-06632-y