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Performance of AI approaches for COVID-19 diagnosis using chest CT scans: the impact of architecture and dataset = Leistungsfähigkeit von KI-Methoden zur COVID-19-Diagnose mittels Thorax-CT: Der Einfluss von KI-Architektur und Datensätzen

AI is emerging as a promising tool for diagnosing COVID-19 based on chest CT scans. The aim of this study was the comparison of AI models for COVID-19 diagnosis. Therefore, we: (1) trained three distinct AI models for classifying COVID-19 and non-COVID-19 pneumonia (nCP) using a large, clinically re...

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Hauptverfasser: Jaiswal, Astha (VerfasserIn) , Fervers, Philipp (VerfasserIn) , Meng, Fanyang (VerfasserIn) , Zhang, Huimao (VerfasserIn) , Móré, Dorottya (VerfasserIn) , Giannakis, Athanasios (VerfasserIn) , Wailzer, Jasmin (VerfasserIn) , Bucher, Andreas Michael (VerfasserIn) , Maintz, David (VerfasserIn) , Kottlors, Jonathan (VerfasserIn) , Shahzad, Rahil (VerfasserIn) , Persigehl, Thorsten (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 29. April 2025
In: RöFo
Year: 2025, Pages: [1-14]
ISSN:1438-9010
DOI:10.1055/a-2577-3928
Online-Zugang:Verlag, kostenfrei, Volltext: https://doi.org/10.1055/a-2577-3928
Verlag, kostenfrei, Volltext: http://www.thieme-connect.de/DOI/DOI?10.1055/a-2577-3928
Volltext
Verfasserangaben:Astha Jaiswal, Philipp Fervers, Fanyang Meng, Huimao Zhang, Dorottya Móré, Athanasios Giannakis, Jasmin Wailzer, Andreas Michael Bucher, David Maintz, Jonathan Kottlors, Rahil Shahzad, Thorsten Persigehl
Beschreibung
Zusammenfassung:AI is emerging as a promising tool for diagnosing COVID-19 based on chest CT scans. The aim of this study was the comparison of AI models for COVID-19 diagnosis. Therefore, we: (1) trained three distinct AI models for classifying COVID-19 and non-COVID-19 pneumonia (nCP) using a large, clinically relevant CT dataset, (2) evaluated the models’ performance using an independent test set, and (3) compared the models both algorithmically and experimentally. In this multicenter multi-vendor study, we collected n=1591 chest CT scans of COVID-19 (n=762) and nCP (n=829) patients from China and Germany. In Germany, the data was collected from three RACOON sites. We trained and validated three COVID-19 AI models with different architectures: COVNet based on 2D-CNN, DeCoVnet based on 3D-CNN, and AD3D-MIL based on 3D-CNN with attention module. 991 CT scans were used for training the AI models using 5-fold cross-validation. 600 CT scans from 6 different centers were used for independent testing. The models’ performance was evaluated using accuracy (Acc), sensitivity (Se), and specificity (Sp). The average validation accuracy of the COVNet, DeCoVnet, and AD3D-MIL models over the 5 folds was 80.9%, 82.0%, and 84.3%, respectively. On the independent test set with n=600 CT scans, COVNet yielded Acc=76.6%, Se=67.8%, Sp=85.7%; DeCoVnet provided Acc=75.1%, Se=61.2%, Sp=89.7%; and AD3D-MIL achieved Acc=73.9%, Se=57.7%, Sp=90.8%. The classification performance of the evaluated AI models is highly dependent on the training data rather than the architecture itself. Our results demonstrate a high specificity and moderate sensitivity. The AI classification models should not be used unsupervised but could potentially assist radiologists in COVID-19 and nCP identification.
Beschreibung:Gesehen am 03.11.2025
Beschreibung:Online Resource
ISSN:1438-9010
DOI:10.1055/a-2577-3928

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