Tebentafusp induces a T-cell-driven rash in melanocyte-bearing skin as an adverse event consistent with the mechanism of action

Tebentafusp is a gp100xCD3-bispecific ImmTAC designed to redirect polyclonal T cells against cells presenting the melanocyte lineage-specific antigen …

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Bibliographic Details
Main Authors: Hassel, Jessica C. (Author) , Stanhope, Sarah (Author) , Greenshields-Watson, Alexander (Author) , Machiraju, Devayani (Author) , Enk, Alexander (Author) , Holland, Christopher (Author) , Abdullah, Shaad E. (Author) , Benlahrech, Adel (Author) , Orloff, Marlana (Author) , Nathan, Paul (Author) , Piperno-Neumann, Sophie (Author) , Staeger, Ramon (Author) , Dummer, Reinhard (Author) , Meier-Schiesser, Barbara (Author)
Format: Article (Journal)
Language:English
Published: March 2025
In: The journal of investigative dermatology
Year: 2025, Volume: 145, Issue: 3, Pages: 559-572.e9
ISSN:1523-1747
DOI:10.1016/j.jid.2024.03.048
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.1016/j.jid.2024.03.048
Verlag, kostenfrei, Volltext: https://www.sciencedirect.com/science/article/pii/S0022202X24018864
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Author Notes:Jessica C. Hassel, Sarah Stanhope, Alexander Greenshields-Watson, Devayani Machiraju, Alexander Enk, Christopher Holland, Shaad E. Abdullah, Adel Benlahrech, Marlana Orloff, Paul Nathan, Sophie Piperno-Neumann, Ramon Staeger, Reinhard Dummer and Barbara Meier-Schiesser
Description
Summary:Tebentafusp is a gp100xCD3-bispecific ImmTAC designed to redirect polyclonal T cells against cells presenting the melanocyte lineage-specific antigen …
Item Description:Online veröffentlicht: 15. Juli 2024, Artikelversion: 20. Februar 2025
Gesehen am 18.11.2025
Physical Description:Online Resource
ISSN:1523-1747
DOI:10.1016/j.jid.2024.03.048