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(68Ga)Ga-FAPI-46 PET/MRT unveils lymph node metastases and changes treatment strategy in recurrent advanced high-grade serous ovarian carcinoma patient

High-grade serous ovarian carcinoma (HGOC) is frequently diagnosed at an advanced stage, leading to high recurrence rates. This case report highlights the utility of [68Ga]Ga-FAPI-46 PET/MRI in detecting previously unidentified lymph node metastases in a 75-year-old woman with recurrent HGOC, which...

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Bibliographic Details
Main Authors: Prochiner, Marie (Author) , Hinterberger, Anna (Author) , Wängler, Björn (Author) , Marmé, Frederik (Author) , Grawe, Freba (Author)
Format: Article (Journal)
Language:English
Published: September 2025
In: Clinical nuclear medicine
Year: 2025, Volume: 50, Issue: 9, Pages: 873-874
ISSN:1536-0229
DOI:10.1097/RLU.0000000000005871
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1097/RLU.0000000000005871
Verlag, lizenzpflichtig, Volltext: https://journals.lww.com/nuclearmed/abstract/2025/09000/_68ga_ga_fapi_46_pet_mrt_unveils_lymph_node.17.aspx
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Author Notes:Marie Prochiner, MS, Anna Hinterberger, MD,Björn Wängler, Frederik Marmé, MD, Freba Grawe, MD
Description
Summary:High-grade serous ovarian carcinoma (HGOC) is frequently diagnosed at an advanced stage, leading to high recurrence rates. This case report highlights the utility of [68Ga]Ga-FAPI-46 PET/MRI in detecting previously unidentified lymph node metastases in a 75-year-old woman with recurrent HGOC, which altered the treatment strategy. The imaging revealed increased [68Ga]Ga-FAPI-46 uptake in nonenlarged mediastinal and left perihilar lymph nodes, reclassifying the patient from FIGO IIIb to FIGO stage IV and prompting a change in therapeutic management.
Item Description:Im Titel steht der Ausdruck [68Ga] in eckigen Klammern, 68 ist dabei hochgestellt
Gesehen am 20.11.2025
Physical Description:Online Resource
ISSN:1536-0229
DOI:10.1097/RLU.0000000000005871

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