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Neutrophil extracellular traps drive peritoneal inflammation and tissue remodeling in pediatric peritoneal dialysis

Peritoneal dialysis (PD) sustains children with chronic kidney disease stage 5 (CKD5) but promotes peritoneal membrane remodeling. Neutrophil extracellular traps (NETs) orchestrate antimicrobial defense and sterile inflammation; their involvement in PD-induced transformation is unknown.

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Bibliographic Details
Main Authors: Dücker, Charlotte Maria (Author) , Herrmann, Martin (Author) , Boettcher, Susanne (Author) , Bauer-Carmona, Sarah (Author) , Schild, Raphael-Sebastian (Author) , Schönfeld, Lavinia (Author) , Raluy, Laia Pagerols (Author) , Reinshagen, Konrad (Author) , Schmitt, Claus P. (Author) , Bartosova, Maria (Author) , Boettcher, Michael (Author)
Format: Article (Journal)
Language:English
Published: 18 October 2025
In: Pediatric nephrology

ISSN:1432-198X
DOI:10.1007/s00467-025-07003-w
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.1007/s00467-025-07003-w
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Author Notes:Charlotte Maria Dücker, Martin Herrmann, Susanne Boettcher, Sarah Bauer-Carmona, Raphael-Sebastian Schild, Lavinia Schönfeld, Laia Pagerols Raluy, Konrad Reinshagen, Claus Peter Schmitt, Maria Bartosova Medvid, Michael Boettcher
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Summary:Peritoneal dialysis (PD) sustains children with chronic kidney disease stage 5 (CKD5) but promotes peritoneal membrane remodeling. Neutrophil extracellular traps (NETs) orchestrate antimicrobial defense and sterile inflammation; their involvement in PD-induced transformation is unknown.
Item Description:Gesehen am 24.11.2025
Physical Description:Online Resource
ISSN:1432-198X
DOI:10.1007/s00467-025-07003-w

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