From nucleoporins to nuclear pore complexes

One of the largest supramolecular assemblies in the eukaryotic cell, the nuclear pore complex, is now being dissected into its numerous molecular constituents. The combined use of biochemistry and genetics in yeast has made this rapid development possible. Although less is known about vertebrate nuc...

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Bibliographic Details
Main Authors: Doye, Valérie (Author) , Hurt, Ed (Author)
Format: Article (Journal)
Language:English
Published: June 1997
In: Current opinion in cell biology
Year: 1997, Volume: 9, Issue: 3, Pages: 401-411
ISSN:1879-0410
DOI:10.1016/S0955-0674(97)80014-2
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1016/S0955-0674(97)80014-2
Verlag, lizenzpflichtig, Volltext: https://www.sciencedirect.com/science/article/pii/S0955067497800142
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Author Notes:Valérie Doye and Ed Hurt
Description
Summary:One of the largest supramolecular assemblies in the eukaryotic cell, the nuclear pore complex, is now being dissected into its numerous molecular constituents. The combined use of biochemistry and genetics in yeast has made this rapid development possible. Although less is known about vertebrate nucleoporins, the first clues are now emerging about their in vivo function also. Much remains to be learned about nuclear pore complex assembly and function, however.
Item Description:Elektronische Reproduktion der Druck-Ausgabe 11. Februar 2002
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Physical Description:Online Resource
ISSN:1879-0410
DOI:10.1016/S0955-0674(97)80014-2