Primary CD34+ cells of patients with vacuoles, E1 enzyme, X-linked, autoinflammatory, somatic (VEXAS) syndrome are highly sensitive to targeted treatment with TAK-243: research letter
Gespeichert in:
| Hauptverfasser: | , , , , , , , , , , , , , , , , , , , , , |
|---|---|
| Dokumenttyp: | Article (Journal) Editorial |
| Sprache: | Englisch |
| Veröffentlicht: |
December 2025
|
| In: |
British journal of haematology
Year: 2025, Jahrgang: 207, Heft: 6, Pages: 2558-2562 |
| ISSN: | 1365-2141 |
| DOI: | 10.1111/bjh.70203 |
| Online-Zugang: | Verlag, kostenfrei, Volltext: https://doi.org/10.1111/bjh.70203 Verlag, kostenfrei, Volltext: https://onlinelibrary.wiley.com/doi/abs/10.1111/bjh.70203 
|
| Verfasserangaben: | Daniel Nowak, Marie Demmerle, Alessa Klär, Alexander Streuer, Vladimir Riabov, Eva Altrock, Felicitas Rapp, Ann-Christin Belzer, Teresa Klink, Meret Hahn, Franziska Hofmann, Verena Nowak, Nadine Weimer, Julia Obländer, Iris Palme, Melda Göl, Ali Darwich, Laurenz Steiner, Mohammed Abba, Georgia Metzgeroth, Wolf-Karsten Hofmann, Nanni Schmitt |
MARC
| LEADER | 00000caa a2200000 c 4500 | ||
|---|---|---|---|
| 001 | 194243555X | ||
| 003 | DE-627 | ||
| 005 | 20260126112106.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 251125s2025 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1111/bjh.70203 |2 doi | |
| 035 | |a (DE-627)194243555X | ||
| 035 | |a (DE-599)KXP194243555X | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 33 |2 sdnb | ||
| 084 | |a 33 |2 sdnb | ||
| 100 | 1 | |a Nowak, Daniel |d 1976- |e VerfasserIn |0 (DE-588)131932063 |0 (DE-627)51618041X |0 (DE-576)298844540 |4 aut | |
| 245 | 1 | 0 | |a Primary CD34+ cells of patients with vacuoles, E1 enzyme, X-linked, autoinflammatory, somatic (VEXAS) syndrome are highly sensitive to targeted treatment with TAK-243 |b research letter |c Daniel Nowak, Marie Demmerle, Alessa Klär, Alexander Streuer, Vladimir Riabov, Eva Altrock, Felicitas Rapp, Ann-Christin Belzer, Teresa Klink, Meret Hahn, Franziska Hofmann, Verena Nowak, Nadine Weimer, Julia Obländer, Iris Palme, Melda Göl, Ali Darwich, Laurenz Steiner, Mohammed Abba, Georgia Metzgeroth, Wolf-Karsten Hofmann, Nanni Schmitt |
| 246 | 3 | 3 | |a Primary CD34 + cells of patients with vacuoles, E1 enzyme, X-linked, autoinflammatory, somatic (VEXAS) syndrome are highly sensitive to targeted treatment with TAK-243 |
| 264 | 1 | |c December 2025 | |
| 300 | |b Diagramme | ||
| 300 | |a 5 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Im Titel ist das Plus-Symbol hochgestellt | ||
| 500 | |a Erstmals veröffentlicht: 12. Oktober 2025 | ||
| 500 | |a Gesehen am 25.11.2025 | ||
| 650 | 4 | |a MDS | |
| 650 | 4 | |a pevonedistat | |
| 650 | 4 | |a TAK-243 | |
| 650 | 4 | |a VEXAS syndrome | |
| 700 | 1 | |a Demmerle, Marie |d 1999- |e VerfasserIn |0 (DE-588)1355116864 |0 (DE-627)1916188702 |4 aut | |
| 700 | 1 | |a Klär, Alessa |d 1997- |e VerfasserIn |0 (DE-588)1370508824 |0 (DE-627)1929680201 |4 aut | |
| 700 | 1 | |a Streuer, Alexander |d 1994- |e VerfasserIn |0 (DE-588)1237642302 |0 (DE-627)1764370198 |4 aut | |
| 700 | 1 | |a Riabov, Vladimir |d 1983- |e VerfasserIn |0 (DE-588)1018515623 |0 (DE-627)690621361 |0 (DE-576)354034561 |4 aut | |
| 700 | 1 | |a Altrock, Eva |d 1984- |e VerfasserIn |0 (DE-588)1139306588 |0 (DE-627)897058607 |0 (DE-576)493229027 |4 aut | |
| 700 | 1 | |a Rapp, Felicitas |e VerfasserIn |0 (DE-588)1186995858 |0 (DE-627)1666277428 |4 aut | |
| 700 | 1 | |a Belzer, Ann-Christin |d 1999- |e VerfasserIn |0 (DE-588)1382510640 |0 (DE-627)1942437137 |4 aut | |
| 700 | 1 | |a Klink, Teresa |d 2001- |e VerfasserIn |0 (DE-588)1382510713 |0 (DE-627)1942437358 |4 aut | |
| 700 | 1 | |a Hahn, Meret |d 1998- |e VerfasserIn |0 (DE-588)1382510837 |0 (DE-627)1942437633 |4 aut | |
| 700 | 1 | |a Hofmann, Franziska |e VerfasserIn |0 (DE-588)1296734609 |0 (DE-627)1853185310 |4 aut | |
| 700 | 1 | |a Nowak, Verena |d 1981- |e VerfasserIn |0 (DE-588)1033389986 |0 (DE-627)741149680 |0 (DE-576)380986175 |4 aut | |
| 700 | 1 | |a Weimer, Nadine |d 1993- |e VerfasserIn |0 (DE-588)1237661013 |0 (DE-627)1764544277 |4 aut | |
| 700 | 1 | |a Obländer, Julia |d 1984- |e VerfasserIn |0 (DE-588)1033921459 |0 (DE-627)743670752 |0 (DE-576)381601609 |4 aut | |
| 700 | 1 | |a Palme, Iris |d 1969- |e VerfasserIn |0 (DE-588)1163571024 |0 (DE-627)1027890113 |0 (DE-576)508058570 |4 aut | |
| 700 | 1 | |a Göl, Melda |e VerfasserIn |0 (DE-588)1296735699 |0 (DE-627)1853186392 |4 aut | |
| 700 | 1 | |a Darwich, Ali |d 1986- |e VerfasserIn |0 (DE-588)1235828840 |0 (DE-627)1760984507 |4 aut | |
| 700 | 1 | |a Steiner, Laurenz |d 1991- |e VerfasserIn |0 (DE-588)1235423433 |0 (DE-627)1760468452 |4 aut | |
| 700 | 1 | |a Abba, Mohammed L. |d 1974- |e VerfasserIn |0 (DE-588)1024986101 |0 (DE-627)720854369 |0 (DE-576)369801407 |4 aut | |
| 700 | 1 | |a Metzgeroth, Georgia |d 1972- |e VerfasserIn |0 (DE-588)1051897661 |0 (DE-627)786986832 |0 (DE-576)407534075 |4 aut | |
| 700 | 1 | |a Hofmann, Wolf-Karsten |d 1967- |e VerfasserIn |0 (DE-588)114154635 |0 (DE-627)691208751 |0 (DE-576)351568336 |4 aut | |
| 700 | 1 | |a Schmitt, Nanni |d 1991- |e VerfasserIn |0 (DE-588)1237642744 |0 (DE-627)1764370805 |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t British journal of haematology |d Oxford [u.a.] : Wiley-Blackwell, 1955 |g 207(2025), 6 vom: Dez., Seite 2558-2562 |h Online-Ressource |w (DE-627)269758941 |w (DE-600)1475751-5 |w (DE-576)09113997X |x 1365-2141 |7 nnas |a Primary CD34+ cells of patients with vacuoles, E1 enzyme, X-linked, autoinflammatory, somatic (VEXAS) syndrome are highly sensitive to targeted treatment with TAK-243 research letter |
| 773 | 1 | 8 | |g volume:207 |g year:2025 |g number:6 |g month:12 |g pages:2558-2562 |g extent:5 |a Primary CD34+ cells of patients with vacuoles, E1 enzyme, X-linked, autoinflammatory, somatic (VEXAS) syndrome are highly sensitive to targeted treatment with TAK-243 research letter |
| 856 | 4 | 0 | |u https://doi.org/10.1111/bjh.70203 |x Verlag |x Resolving-System |z kostenfrei |3 Volltext |7 0 |
| 856 | 4 | 0 | |u https://onlinelibrary.wiley.com/doi/abs/10.1111/bjh.70203 |x Verlag |z kostenfrei |3 Volltext |7 0 |
| 951 | |a AR | ||
| 992 | |a 20251125 | ||
| 992 | |a 20251125 | ||
| 993 | |a Editorial | ||
| 993 | |a Editorial | ||
| 994 | |a 2025 | ||
| 994 | |a 2025 | ||
| 998 | |g 1237642744 |a Schmitt, Nanni |m 1237642744:Schmitt, Nanni |d 60000 |d 61200 |e 60000PS1237642744 |e 61200PS1237642744 |k 0/60000/ |k 1/60000/61200/ |p 22 |y j | ||
| 998 | |g 114154635 |a Hofmann, Wolf-Karsten |m 114154635:Hofmann, Wolf-Karsten |d 60000 |d 61200 |e 60000PH114154635 |e 61200PH114154635 |k 0/60000/ |k 1/60000/61200/ |p 21 | ||
| 998 | |g 1051897661 |a Metzgeroth, Georgia |m 1051897661:Metzgeroth, Georgia |d 60000 |d 61200 |e 60000PM1051897661 |e 61200PM1051897661 |k 0/60000/ |k 1/60000/61200/ |p 20 | ||
| 998 | |g 1024986101 |a Abba, Mohammed L. |m 1024986101:Abba, Mohammed L. |d 60000 |d 61200 |d 60000 |e 60000PA1024986101 |e 61200PA1024986101 |e 60000PA1024986101 |k 0/60000/ |k 1/60000/61200/ |k 0/60000/ |p 19 | ||
| 998 | |g 1235423433 |a Steiner, Laurenz |m 1235423433:Steiner, Laurenz |d 60000 |e 60000PS1235423433 |k 0/60000/ |p 18 | ||
| 998 | |g 1235828840 |a Darwich, Ali |m 1235828840:Darwich, Ali |d 60000 |d 62400 |e 60000PD1235828840 |e 62400PD1235828840 |k 0/60000/ |k 1/60000/62400/ |p 17 | ||
| 998 | |g 1296735699 |a Göl, Melda |m 1296735699:Göl, Melda |p 16 | ||
| 998 | |g 1163571024 |a Palme, Iris |m 1163571024:Palme, Iris |d 60000 |d 61200 |e 60000PP1163571024 |e 61200PP1163571024 |k 0/60000/ |k 1/60000/61200/ |p 15 | ||
| 998 | |g 1033921459 |a Obländer, Julia |m 1033921459:Obländer, Julia |d 60000 |e 60000PO1033921459 |k 0/60000/ |p 14 | ||
| 998 | |g 1237661013 |a Weimer, Nadine |m 1237661013:Weimer, Nadine |d 60000 |e 60000PW1237661013 |k 0/60000/ |p 13 | ||
| 998 | |g 1033389986 |a Nowak, Verena |m 1033389986:Nowak, Verena |d 60000 |d 61200 |e 60000PN1033389986 |e 61200PN1033389986 |k 0/60000/ |k 1/60000/61200/ |p 12 | ||
| 998 | |g 1296734609 |a Hofmann, Franziska |m 1296734609:Hofmann, Franziska |d 60000 |e 60000PH1296734609 |k 0/60000/ |p 11 | ||
| 998 | |g 1382510837 |a Hahn, Meret |m 1382510837:Hahn, Meret |d 60000 |e 60000PH1382510837 |k 0/60000/ |p 10 | ||
| 998 | |g 1382510713 |a Klink, Teresa |m 1382510713:Klink, Teresa |d 60000 |e 60000PK1382510713 |k 0/60000/ |p 9 | ||
| 998 | |g 1382510640 |a Belzer, Ann-Christin |m 1382510640:Belzer, Ann-Christin |d 60000 |e 60000PB1382510640 |k 0/60000/ |p 8 | ||
| 998 | |g 1186995858 |a Rapp, Felicitas |m 1186995858:Rapp, Felicitas |d 60000 |d 61200 |e 60000PR1186995858 |e 61200PR1186995858 |k 0/60000/ |k 1/60000/61200/ |p 7 | ||
| 998 | |g 1139306588 |a Altrock, Eva |m 1139306588:Altrock, Eva |d 60000 |d 61200 |e 60000PA1139306588 |e 61200PA1139306588 |k 0/60000/ |k 1/60000/61200/ |p 6 | ||
| 998 | |g 1237642302 |a Streuer, Alexander |m 1237642302:Streuer, Alexander |d 60000 |d 61200 |e 60000PS1237642302 |e 61200PS1237642302 |k 0/60000/ |k 1/60000/61200/ |p 4 | ||
| 998 | |g 1370508824 |a Klär, Alessa |m 1370508824:Klär, Alessa |d 60000 |e 60000PK1370508824 |k 0/60000/ |p 3 | ||
| 998 | |g 1355116864 |a Demmerle, Marie |m 1355116864:Demmerle, Marie |d 60000 |e 60000PD1355116864 |k 0/60000/ |p 2 | ||
| 998 | |g 131932063 |a Nowak, Daniel |m 131932063:Nowak, Daniel |d 60000 |d 61200 |d 60000 |e 60000PN131932063 |e 61200PN131932063 |e 60000PN131932063 |k 0/60000/ |k 1/60000/61200/ |k 0/60000/ |p 1 |x j | ||
| 999 | |a KXP-PPN194243555X |e 4813250270 | ||
| 999 | |a KXP-PPN194243555X |e 4813248136 | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"title":[{"title":"Primary CD34+ cells of patients with vacuoles, E1 enzyme, X-linked, autoinflammatory, somatic (VEXAS) syndrome are highly sensitive to targeted treatment with TAK-243","subtitle":"research letter","title_sort":"Primary CD34+ cells of patients with vacuoles, E1 enzyme, X-linked, autoinflammatory, somatic (VEXAS) syndrome are highly sensitive to targeted treatment with TAK-243"}],"language":["eng"],"titleAlt":[{"title":"Primary CD34 + cells of patients with vacuoles, E1 enzyme, X-linked, autoinflammatory, somatic (VEXAS) syndrome are highly sensitive to targeted treatment with TAK-243"}],"person":[{"given":"Daniel","display":"Nowak, Daniel","family":"Nowak","role":"aut"},{"role":"aut","family":"Demmerle","display":"Demmerle, Marie","given":"Marie"},{"family":"Klär","given":"Alessa","display":"Klär, Alessa","role":"aut"},{"family":"Streuer","display":"Streuer, Alexander","given":"Alexander","role":"aut"},{"role":"aut","family":"Riabov","given":"Vladimir","display":"Riabov, Vladimir"},{"role":"aut","family":"Altrock","given":"Eva","display":"Altrock, Eva"},{"role":"aut","display":"Rapp, Felicitas","given":"Felicitas","family":"Rapp"},{"role":"aut","family":"Belzer","display":"Belzer, Ann-Christin","given":"Ann-Christin"},{"family":"Klink","display":"Klink, Teresa","given":"Teresa","role":"aut"},{"family":"Hahn","given":"Meret","display":"Hahn, Meret","role":"aut"},{"role":"aut","family":"Hofmann","display":"Hofmann, Franziska","given":"Franziska"},{"role":"aut","display":"Nowak, Verena","given":"Verena","family":"Nowak"},{"given":"Nadine","display":"Weimer, Nadine","family":"Weimer","role":"aut"},{"role":"aut","family":"Obländer","given":"Julia","display":"Obländer, Julia"},{"role":"aut","family":"Palme","given":"Iris","display":"Palme, Iris"},{"role":"aut","family":"Göl","given":"Melda","display":"Göl, Melda"},{"role":"aut","family":"Darwich","given":"Ali","display":"Darwich, Ali"},{"given":"Laurenz","display":"Steiner, Laurenz","family":"Steiner","role":"aut"},{"role":"aut","given":"Mohammed L.","display":"Abba, Mohammed L.","family":"Abba"},{"family":"Metzgeroth","given":"Georgia","display":"Metzgeroth, Georgia","role":"aut"},{"role":"aut","display":"Hofmann, Wolf-Karsten","given":"Wolf-Karsten","family":"Hofmann"},{"given":"Nanni","display":"Schmitt, Nanni","family":"Schmitt","role":"aut"}],"name":{"displayForm":["Daniel Nowak, Marie Demmerle, Alessa Klär, Alexander Streuer, Vladimir Riabov, Eva Altrock, Felicitas Rapp, Ann-Christin Belzer, Teresa Klink, Meret Hahn, Franziska Hofmann, Verena Nowak, Nadine Weimer, Julia Obländer, Iris Palme, Melda Göl, Ali Darwich, Laurenz Steiner, Mohammed Abba, Georgia Metzgeroth, Wolf-Karsten Hofmann, Nanni Schmitt"]},"origin":[{"dateIssuedKey":"2025","dateIssuedDisp":"December 2025"}],"recId":"194243555X","note":["Im Titel ist das Plus-Symbol hochgestellt","Erstmals veröffentlicht: 12. Oktober 2025","Gesehen am 25.11.2025"],"relHost":[{"title":[{"subtitle":"BJHaem : an official journal of the British Society for Haematology","title_sort":"British journal of haematology","title":"British journal of haematology"}],"origin":[{"publisher":"Wiley-Blackwell ; Blackwell Science ; Blackwell","dateIssuedDisp":"1955-","dateIssuedKey":"1955","publisherPlace":"Oxford [u.a.] ; Oxford ; Oxford [u.a.]"}],"name":{"displayForm":["ed. R. B. Thompson [u.a.]"]},"corporate":[{"role":"isb","display":"British Society for Haematology"},{"display":"European Hematology Association","role":"isb"}],"note":["Gesehen am 08.05.08"],"id":{"zdb":["1475751-5"],"doi":["10.1111/(ISSN)1365-2141"],"issn":["1365-2141"],"eki":["269758941"]},"part":{"issue":"6","extent":"5","pages":"2558-2562","year":"2025","volume":"207","text":"207(2025), 6 vom: Dez., Seite 2558-2562"},"physDesc":[{"extent":"Online-Ressource"}],"titleAlt":[{"title":"the official journal of the British Society of Haematology"},{"title":"BJH ; the official journal of the British Society for Haematology"}],"language":["eng"],"recId":"269758941","disp":"Primary CD34+ cells of patients with vacuoles, E1 enzyme, X-linked, autoinflammatory, somatic (VEXAS) syndrome are highly sensitive to targeted treatment with TAK-243 research letterBritish journal of haematology","pubHistory":["1.1955 -"],"type":{"bibl":"periodical","media":"Online-Ressource"}}],"physDesc":[{"noteIll":"Diagramme","extent":"5 S."}],"id":{"doi":["10.1111/bjh.70203"],"eki":["194243555X"]},"type":{"bibl":"article-journal","media":"Online-Ressource"}} | ||
| SRT | |a NOWAKDANIEPRIMARYCD32025 | ||