Congenital diaphragmatic hernia: what are the priorities for the next 20 years?
Advances in clinical care, biomedical research, and health advocacy have significantly improved survival and quality of life across the lifespan. To sustain and accelerate this progress, it is essential to define clear goals for the future. Congenital diaphragmatic hernia (CDH), one of the most comm...
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| Main Authors: | , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
October 2025
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| In: |
Seminars in fetal & neonatal medicine
Year: 2025, Volume: 30, Issue: 3, Pages: 1-8 |
| ISSN: | 1878-0946 |
| DOI: | 10.1016/j.siny.2025.101658 |
| Online Access: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1016/j.siny.2025.101658 Verlag, lizenzpflichtig, Volltext: https://www.sciencedirect.com/science/article/pii/S1744165X25000526 
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| Author Notes: | David McCulley, Florian Kipfmueller, Neil Patel |
| Summary: | Advances in clinical care, biomedical research, and health advocacy have significantly improved survival and quality of life across the lifespan. To sustain and accelerate this progress, it is essential to define clear goals for the future. Congenital diaphragmatic hernia (CDH), one of the most common and severe congenital malformations, serves as a model condition where coordinated efforts in clinical care, research, and advocacy have led to important advances in understanding disease mechanisms and improving outcomes. Reflecting on this progress reveals several key themes, including the value of disease modelling, novel therapeutic strategies, and sustained innovation. Achieving a better future for people with CDH will require strategic prioritization of research, engagement of methodological expertise, addressing practical barriers, and promotion of collaboration. We propose that coordinated global efforts - including for example the creation of an international research platform, leveraging technological advances, and raising the visibility of CDH - will empower clinicians, researchers, and the CDH community to drive continued progress. |
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| Item Description: | Online verfügbar: 26. August 2025, Artikelversion: 16. Oktober 2025 Gesehen am 03.12.2025 |
| Physical Description: | Online Resource |
| ISSN: | 1878-0946 |
| DOI: | 10.1016/j.siny.2025.101658 |