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Imposed work of breathing of 16 neonatal CPAP-devices using different mechanisms of CPAP generation

Failure of continuous positive airway pressure (CPAP) in preterm infants may result from respiratory exhaustion, potentially also evoked by the CPAP device’s imposed work of breathing (iWOB). This study investigated in-vitro the iWOB of 16 CPAP-devices in four simulated neonatal scenarios with focus...

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Main Authors: Sterzik, Hanna (Author) , Arand, Joerg (Author) , Schwarz, Christoph (Author) , Kumpf, Matthias (Author) , Wald, Martin (Author) , Kribs, Angela (Author) , Lauth, Wanda (Author) , Gross, Maximilian (Author) , Poets, Christian F. (Author) , Haase, Bianca (Author)
Format: Article (Journal)
Language:English
Published: 25 July 2025
In: Pediatric research
Year: 2025, Pages: 1-6
ISSN:1530-0447
DOI:10.1038/s41390-025-04265-w
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.1038/s41390-025-04265-w
Verlag, kostenfrei, Volltext: https://www.nature.com/articles/s41390-025-04265-w
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Author Notes:Hanna Sterzik, Joerg Arand, Christoph E. Schwarz, Matthias Kumpf, Martin Wald, Angela Kribs, Wanda Lauth, Maximilian Gross, Christian F. Poets and Bianca Haase
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Summary:Failure of continuous positive airway pressure (CPAP) in preterm infants may result from respiratory exhaustion, potentially also evoked by the CPAP device’s imposed work of breathing (iWOB). This study investigated in-vitro the iWOB of 16 CPAP-devices in four simulated neonatal scenarios with focus on the impact of different mechanisms of CPAP-generation.
Item Description:Gesehen am 08.12.2025
Physical Description:Online Resource
ISSN:1530-0447
DOI:10.1038/s41390-025-04265-w

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