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Common factors in altered states: understanding psychedelic therapy through the lens of Grawe’s general change mechanisms$dpsychological review

Psychedelic therapy is commonly understood as a form of psychotherapy. However, despite promising results from clinical trials, scientific progress has been hindered by a lack of theoretical integration between the fields of psychedelic and psychotherapy research. This article seeks to bridge this d...

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Main Authors: Wolff, Max (Author) , Rutrecht, Hans (Author) , Mertens, Lea Julia (Author) , Meijer, Andy A. (Author) , Beck, Jessica (Author) , Pérez, Sergio (Author) , Gründer, Gerhard (Author) , Dziobek, Isabel (Author) , Jungaberle, Henrik (Author)
Format: Article (Journal)
Language:English
Published: 2025
In: Psychological review
Year: 2025, Volume: 132, Issue: 6, Pages: 1467-1492
ISSN:1939-1471
DOI:10.1037/rev0000589
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1037/rev0000589
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Author Notes:Max Wolff, Hans Rutrecht, Lea J. Mertens, Andy A. Meijer, Jessica Beck, Sergio Pérez, Gerhard Gründer, Isabel Dziobek, and Henrik Jungaberle
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Summary:Psychedelic therapy is commonly understood as a form of psychotherapy. However, despite promising results from clinical trials, scientific progress has been hindered by a lack of theoretical integration between the fields of psychedelic and psychotherapy research. This article seeks to bridge this divide by outlining a transtheoretical understanding of psychedelic-occasioned psychological change based on Klaus Grawe’s model of general change mechanisms—an empirically grounded framework of psychotherapeutic “common factors” that emphasizes therapeutic experiences and change processes. Drawing on extensive evidence from psychedelic research, we argue that the efficacy of psychedelic therapy is ultimately mediated by the same five general change mechanisms that underlie all effective psychotherapies: (1) resource activation, (2) therapeutic relationship, (3) problem actuation, (4) clarification, and (5) mastery. Implications for clinical practice, training, and future research are discussed. (PsycInfo Database Record (c) 2025 APA, all rights reserved)
Item Description:Gesehen am 09.12.2025
Physical Description:Online Resource
ISSN:1939-1471
DOI:10.1037/rev0000589

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