Nationwide implementation of the international multidisciplinary best-practice for locally advanced pancreatic cancer (PREOPANC-4): study protocol

The introduction of (m)FOLFIRINOX and gemcitabine-nab-paclitaxel has changed the perspective for patients with locally advanced pancreatic cancer (LAPC). Consequently, in experienced centres 23% of patients with LAPC undergo a resection with 5-year overall survival (OS) rates of up to 25%. In the Ne...

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Main Authors:	Stoop, Thomas F. (Author) , Seelen, L. W. F. (Author) , Land, F. R. van 't (Author) , Hout, A. C. van der (Author) , Scheepens, J. C. M. (Author) , Ali, M. (Author) , Stiggelbout, A. M. (Author) , Kolk, B. M. van der (Author) , Bonsing, B. A. (Author) , Lips, D. J. (Author) , Groot, D. J. A. de (Author) , Veldhuisen, E. van (Author) , Kerver, E. D. (Author) , Manusama, E. R. (Author) , Daams, F. (Author) , Kazemier, G. (Author) , Cirkel, G. A. (Author) , Tienhoven, G. van (Author) , Patijn, G. A. (Author) , Lelieveld-Rier, H. N. (Author) , de Hingh, I. H. (Author) , van Hellemond, I. E. G. (Author) , Wijsman, J. H. (Author) , Erdmann, J. I. (Author) , Mieog, J. S. D. (Author) , Vos-Geelen, J. de (Author) , Groot, J. W. B. de (Author) , Lutchman, K. R. D. (Author) , Mekenkamp, L. J. (Author) , Kranenburg, L. W. (Author) , Beuk, L. P. M. (Author) , Nijkamp, M. W. (Author) , den Dulk, M. (Author) , Polée, M. B. (Author) , Homs, M. Y. V. (Author) , Wumkes, M. L. (Author) , Stommel, M. W. J. (Author) , Busch, O. R. (Author) , Wilde, R. F. de (Author) , Theijse, R. T. (Author) , Luelmo, S. A. C. (Author) , Festen, S. (Author) , Bollen, T. L. (Author) , Neumann, U. P. (Author) , Meijer, V. E. de (Author) , Draaisma, W. A. (Author) , Groot Koerkamp, B. (Author) , Molenaar, I. Q. (Author) , Wolfgang, C. L. (Author) , Del Chiaro, M. (Author) , Katz, M. G. H. (Author) , Hackert, Thilo (Author) , Rietjens, J. A. C. (Author) , Wilmink, J. W. (Author) , Santvoort, H. C. van (Author) , Eijck, C. H. J. van (Author) , Besselink, M. G. (Author) , Bruynzeel, A. (Author) , Vlijm, A. (Author) , Asseldonk, A. van (Author) , Zonderhuis, B. (Author) , Javed, A.A. (Author) , Sterk, A. (Author) , Schoorlemmer, A. (Author) , Stam, A. (Author) , Nio, C.Y. (Author) , Alphen, E. van (Author) , Laarhoven, H.W.M. van (Author) , Veenendaal, H. van (Author) , Griffioen, I. (Author) , Rompen, I.F. (Author) , Klaase, J.M. (Author) , Los, M. (Author) , Marting, M.F.M.A. (Author) , Liem, M.S.L. (Author) , Peters, J. (Author) , Peters, L.J. (Author) , Garms, Linda (Author) , Walma, M. (Author) , Brada, L.H.J. (Author) , Seijbel, M. (Author) , Hildebrand, N.D. (Author) , Michiels, N. (Author) , Bax, R. (Author) , Dam, R.M. van (Author) , Achten, S. (Author) , Bouwense, S. (Author) , Augustinus, S. (Author) , Rötgerink, S. (Author) , Ravens, T.W. van (Author) , Nieuwenhuijs, V.B. (Author) , te Riele, W.W. (Author)
Format:	Article (Journal)
Language:	English
Published:	February 19, 2025
In:	BMC cancer Year: 2025, Volume: 25, Pages: 1-12
ISSN:	1471-2407
DOI:	10.1186/s12885-025-13554-w
Online Access:	Verlag, kostenfrei, Volltext: https://doi.org/10.1186/s12885-025-13554-w
Author Notes:	T.F. Stoop, L.W.F. Seelen, F.R. van ’t Land, A.C. van der Hout, J.C.M. Scheepens, M. Ali, A.M. Stiggelbout, B.M. van der Kolk, B.A. Bonsing, D.J. Lips, D.J.A. de Groot, E. van Veldhuisen, E.D. Kerver, E.R. Manusama, F. Daams, G. Kazemier, G.A. Cirkel, G. van Tienhoven, G.A. Patijn, H.N. Lelieveld-Rier, I.H. de Hingh, I.E.G. van Hellemond, J.H. Wijsman, J.I. Erdmann, J.S.D. Mieog, J. de Vos-Geelen, J.W.B. de Groot, K.R.D. Lutchman, L.J. Mekenkamp, L.W. Kranenburg, L.P.M. Beuk, M. W. Nijkamp, M. den Dulk, M.B. Polée, M.Y.V. Homs, M.L. Wumkes, M.W.J. Stommel, O.R. Busch, R.F. de Wilde, R.T. Theijse, S.A.C. Luelmo, S. Festen, T.L. Bollen, U.P. Neumann, V.E. de Meijer, W.A. Draaisma, B. Groot Koerkamp, I.Q. Molenaar, C.L. Wolfgang, M. Del Chiaro, M.G.H. Katz, T. Hackert, J.A.C. Rietjens, J.W. Wilmink, H.C. van Santvoort, C.H.J. van Eijck, M.G. Besselink and for the Dutch Pancreatic Cancer Group