Association of prenatal alcohol exposure and prenatal depressive symptoms with offspring hair cortisol in childhood and adolescence

Prenatal alcohol exposure (PAE) and maternal depressive symptoms are associated with hypothalamic-pituitary-adrenal (HPA) axis alterations in the offspring. The present study investigated long-term associations of both risk factors on the offspring’s hair cortisol concentration (HCC) in childhood an...

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Main Authors: Plank, Anne-Christine (Author) , Panaseth-Gehle, Kerstin (Author) , Gerlach, Jennifer (Author) , Mestermann, Stefan (Author) , Fasching, Peter A. (Author) , Beckmann, Matthias W. (Author) , Kratz, Oliver (Author) , Moll, Gunther H. (Author) , Lenz, Bernd (Author) , Kornhuber, Johannes (Author) , Eichler, Anna (Author)
Format: Article (Journal)
Language:English
Published: December 2025
In: BMC psychiatry
Year: 2025, Volume: 25, Issue: 1, Pages: 1-15
ISSN:1471-244X
DOI:10.1186/s12888-025-07559-9
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.1186/s12888-025-07559-9
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Author Notes:Anne-Christine Plank, Kerstin Panaseth-Gehle, Jennifer Gerlach, Stefan Mestermann, Peter A. Fasching, Matthias W. Beckmann, Oliver Kratz, Gunther H. Moll, Bernd Lenz, Johannes Kornhuber, Anna Eichler and IMAC-Mind Konsortium
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Summary:Prenatal alcohol exposure (PAE) and maternal depressive symptoms are associated with hypothalamic-pituitary-adrenal (HPA) axis alterations in the offspring. The present study investigated long-term associations of both risk factors on the offspring’s hair cortisol concentration (HCC) in childhood and adolescence.
Item Description:Gesehen am 09.12.2025
Physical Description:Online Resource
ISSN:1471-244X
DOI:10.1186/s12888-025-07559-9