Spatial and functional dissection of cancer-associated fibroblasts-mediated immune modulation in H. pylori-associated gastric cancer
Cancer-associated fibroblasts (CAFs) are key regulators of the tumor microenvironment, yet their spatial organization and immunomodulatory functions in H. pylori-associated gastric cancer (GC) remain incompletely understood.
Gespeichert in:
| Hauptverfasser: | , , , , , , , , , , , , , , , , , , , , , , , , , , , |
|---|---|
| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
December 2025
|
| In: |
Molecular cancer
Year: 2025, Jahrgang: 24, Heft: 1, Pages: 1-20 |
| ISSN: | 1476-4598 |
| DOI: | 10.1186/s12943-025-02490-9 |
| Online-Zugang: | Verlag, kostenfrei, Volltext: https://doi.org/10.1186/s12943-025-02490-9 |
| Verfasserangaben: | Bonan Chen, Hongzhen Tang, Xiaohong Zheng, Fuda Xie, Peiyao Yu, Yang Lyu, Tiejun Feng, Jialin Wu, Jingya Liu, Yi Xu, Alvin H. K. Cheung, Canbin Fang, Zhangding Wang, Shouyu Wang, Justin Chak Ting Cheung, Yujuan Dong, Ruoxi Tian, Yigan Zhang, Cheng Lu, Chi Chun Wong, Jun Yu, William K. K. Wu, Elke Burgermeister, Man Tong, Fengbin Zhang, Wei Kang, Kam Tong Leung and Ka Fai To |
| Zusammenfassung: | Cancer-associated fibroblasts (CAFs) are key regulators of the tumor microenvironment, yet their spatial organization and immunomodulatory functions in H. pylori-associated gastric cancer (GC) remain incompletely understood. |
|---|---|
| Beschreibung: | Online veröffentlicht: 6. November 2025 Gesehen am 09.12.2025 |
| Beschreibung: | Online Resource |
| ISSN: | 1476-4598 |
| DOI: | 10.1186/s12943-025-02490-9 |