Development and application of an LC-MS/MS method for quantification of fosmidomycin in human and rat plasma
Malaria still poses a significant burden on global health, with millions of cases reported annually and rising resistance to current treatments, emphasizing the need for new therapeutic strategies. Fosmidomycin, initially recognized for its antibacterial properties, has emerged as a promising candid...
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| Hauptverfasser: | , , , , , , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
25 July 2025
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| In: |
Malaria journal
Year: 2025, Jahrgang: 24, Heft: 1, Pages: 1-11 |
| ISSN: | 1475-2875 |
| DOI: | 10.1186/s12936-025-05489-1 |
| Online-Zugang: | Verlag, kostenfrei, Volltext: https://doi.org/10.1186/s12936-025-05489-1 Verlag, kostenfrei, Volltext: https://link.springer.com/article/10.1186/s12936-025-05489-1 |
| Verfasserangaben: | Christoph Pfaffendorf, Keanu D. Sackmann, Johannes Mischlinger, Jean Claude Dejon-Agobé, Oumou Maïga-Ascofaré, Ebenezer Ahenkan, Ayôla Akim Adegnika, Michael Ramharter, Philipp Uhl, Gert Fricker and Sebastian G. Wicha |
| Zusammenfassung: | Malaria still poses a significant burden on global health, with millions of cases reported annually and rising resistance to current treatments, emphasizing the need for new therapeutic strategies. Fosmidomycin, initially recognized for its antibacterial properties, has emerged as a promising candidate in the fight against malaria. |
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| Beschreibung: | Gesehen am 11.12.2025 |
| Beschreibung: | Online Resource |
| ISSN: | 1475-2875 |
| DOI: | 10.1186/s12936-025-05489-1 |