Effect of proton pump inhibitors on occlusion of lumen-apposing metal stents and rate of endoscopic necrosectomies: a Europe-wide multicenter cohort study

Lumen-apposing metal stents (LAMS) are widely used to drain walled-off necrosis (WON). LAMS occlusion is a significant clinical problem and identification of risk factors for LAMS occlusion could contribute to novel preventive strategies. A previous study suggested contradictory effects of proton pu...

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Main Authors: Hamm, Jacob (Author) , Busana, Alzbeta (Author) , Amanzada, Ahmad (Author) , Arlt, Alexander (Author) , Asendorf, Thomas (Author) , Carswell, Samantha (Author) , Denzer, Ulrike (Author) , Elsing, Louis (Author) , Frost, Fabian (Author) , Guilabert, Lucia (Author) , Hamesch, Karim (Author) , Hollenbach, Marcus (Author) , Hegyi, Péter (Author) , Kleger, Alexander (Author) , Krivinka, Jan (Author) , Kunovsky, Lumir (Author) , Meinhardt, Christian (Author) , Phillip, Veit (Author) , Schlosser-Hupf, Sophie (Author) , Sirtl, Simon (Author) , Welsch, Lukas (Author) , Widdern, Julian Cardinal von (Author) , Neesse, Albrecht (Author) , Ammer-Herrmenau, Christoph (Author) , Michl, Patrick (Author)
Format: Article (Journal)
Language:English
Published: 08. Mai 2025
In: Endoscopy
Year: 2025, Volume: 57, Issue: 08, Pages: 829-838
ISSN:1438-8812
DOI:10.1055/a-2569-7056
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.1055/a-2569-7056
Verlag, kostenfrei, Volltext: http://www.thieme-connect.de/DOI/DOI?10.1055/a-2569-7056
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Author Notes:Jacob Hamm, Alzbeta Busana, Ahmad Amanzada, Alexander Arlt, Thomas Asendorf, Samantha Carswell, Ulrike Denzer, Louis Elsing, Fabian Frost, Lucia Guilabert, Karim Hamesch, Marcus Hollenbach, Péter Hegyi, Alexander Kleger, Jan Krivinka, Lumir Kunovsky, Christian Meinhardt, Veit Phillip, Sophie Schlosser-Hupf, Simon Sirtl, Lukas Welsch, Julian Cardinal von Widdern, Albrecht Neesse, Christoph Ammer-Herrmenau, PROTOCOL working Group
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Summary:Lumen-apposing metal stents (LAMS) are widely used to drain walled-off necrosis (WON). LAMS occlusion is a significant clinical problem and identification of risk factors for LAMS occlusion could contribute to novel preventive strategies. A previous study suggested contradictory effects of proton pump inhibitors (PPIs) on occlusion and necrosectomy rates.
Item Description:PROTOCOL working Group: Georg Beyer, Patrick Michl [und viele weitere]
Gesehen am 17.12.2025
Physical Description:Online Resource
ISSN:1438-8812
DOI:10.1055/a-2569-7056