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Get strong to fight childhood cancer - an exercise intervention for children and adolescents undergoing anti-cancer treatment (FORTEe): rationale and design of a randomized controlled exercise trial

Despite substantial advances in treatment, children and adolescents with cancer continue to face high morbidity and health issues, including cancer-related fatigue, treatment-related complications, and physical inactivity. Integrating exercise into pediatric oncology care has emerged as a promising...

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Main Authors: Neu, Marie Astrid (Author) , Dreismickenbecker, Elias (Author) , Lanfranconi, Francesca (Author) , Stössel, Sandra (Author) , Balduzzi, Adriana (Author) , Wright, Peter (Author) , Windsor, Stan (Author) , Wiskemann, Joachim (Author) , El-Rajab, Inaam (Author) , Lucia, Alejandro (Author) , Fiuza-Luces, Carmen (Author) , Mongondry, Rodolf (Author) , Fridh, Martin Kaj (Author) , Spreafico, Filippo (Author) , Konda, Barbara (Author) , Kitanovski, Lidija (Author) , Heißerer, Barbara (Author) , Polak, Marco (Author) , Baader, Tobias (Author) , Bloch, Wilhelm (Author) , Götte, Miriam (Author) , Rizvi, Katie (Author) , Ruckes, Christian (Author) , Paul, Norbert W. (Author) , Faber, Joerg (Author) , Schwalber, Ameli (Author) , Pérol, Olivia (Author) , Larsen, Hanne Bækgaard (Author) , Moriggi, Tommaso Pietro (Author) , Zardo, William (Author) , Bertrand, Amandine (Author) , Wypyrsczyk, Lena (Author) , Kühn, Mareike (Author) , Robinson, Abigale (Author) , Diel, Heidi (Author)
Format: Article (Journal)
Language:English
Published: 07 August 2025
In: BMC cancer
Year: 2025, Volume: 25, Pages: 1-12
ISSN:1471-2407
DOI:10.1186/s12885-025-14489-y
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.1186/s12885-025-14489-y
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Author Notes:Marie Astrid Neu, Elias Dreismickenbecker, Francesca Lanfranconi, Sandra Stössel, Adriana Balduzzi, Peter Wright, Stan Windsor, Joachim Wiskemann, Inaam El-Rajab, Alejandro Lucia, Carmen Fiuza-Luces, Rodolf Mongondry, Martin Kaj Fridh, Filippo Spreafico, Barbara Konda, Lidija Kitanovski, Barbara Heißerer, Marco Polak, Tobias Baader, Wilhelm Bloch, Miriam Götte, on behalf of Network ActiveOncoKids, Katie Rizvi, on behalf of Youth Cancer Europe, Christian Ruckes, Norbert W. Paul, Joerg Faber and on behalf of the FORTEe Consortium
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Summary:Despite substantial advances in treatment, children and adolescents with cancer continue to face high morbidity and health issues, including cancer-related fatigue, treatment-related complications, and physical inactivity. Integrating exercise into pediatric oncology care has emerged as a promising approach to mitigate these burdens during cancer treatment. While preliminary data support its potential to reduce treatment-related side effects and enhance quality of life, robust evidence -especially from large, multicenter trials- remains limited.
Item Description:Gesehen am 19.12.2025
Physical Description:Online Resource
ISSN:1471-2407
DOI:10.1186/s12885-025-14489-y

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