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Early left ventricular diastolic function and disease severity in congenital diaphragmatic hernia

Congenital diaphragmatic hernia (CDH) remains a major cause of neonatal mortality and morbidity. Early systolic left ventricular (LV) dysfunction is well described in CDH, while diastolic impairment remains unexplored. This study aimed to investigate the feasibility LV diastolic function assessment...

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Main Authors: Cantone, Giulia Vanina (Author) , Bhattacharya, Abhijit (Author) , Healy, David (Author) , Levinkopf, Dana (Author) , Massolo, Anna Claudia (Author) , Pugnaloni, Flaminia (Author) , Vento, Giovanni (Author) , Heuchan, Anne Marie (Author) , Kipfmüller, Florian (Author) , Patel, Neil (Author)
Format: Article (Journal)
Language:English
Published: 12 November 2025
In: Pediatric research
Year: 2025, Pages: 1-8
ISSN:1530-0447
DOI:10.1038/s41390-025-04560-6
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.1038/s41390-025-04560-6
Verlag, kostenfrei, Volltext: https://www.nature.com/articles/s41390-025-04560-6
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Author Notes:Giulia Vanina Cantone, Abhijit Bhattacharya, David Healy, Dana Levinkopf, Anna Claudia Massolo, Flaminia Pugnaloni, Giovanni Vento, Anne Marie Heuchan, Florian Kipfmueller and Neil Patel
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Summary:Congenital diaphragmatic hernia (CDH) remains a major cause of neonatal mortality and morbidity. Early systolic left ventricular (LV) dysfunction is well described in CDH, while diastolic impairment remains unexplored. This study aimed to investigate the feasibility LV diastolic function assessment and to evaluate its relationship with clinical severity.
Item Description:Gesehen am 12.01.2026
Physical Description:Online Resource
ISSN:1530-0447
DOI:10.1038/s41390-025-04560-6

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