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Expression and functional evaluation of ABC and SLC transporters in Human Choroid Plexus Papilloma (HIBCPP) cells: a human blood-cerebrospinal fluid barrier model

Human choroid plexus papilloma (HIBCPP) cells derived from choroid plexus papilloma in the lateral ventricle are considered suitable model cells for the blood-cerebrospinal fluid barrier (BCSFB). Therefore, in this study, the transporters expressed in HIBCPP cells were identified, and the functions...

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Main Authors: Kurosawa, Toshiki (Author) , Ohtsuki, Sumio (Author) , Ishikawa, Hiroshi (Author) , Schroten, Horst (Author) , Schwerk, Christian (Author) , Kubo, Yoshiyuki (Author) , Deguchi, Yoshiharu (Author)
Format: Article (Journal)
Language:English
Published: 10 December 2025
In: Pharmaceutical research

ISSN:1573-904X
DOI:10.1007/s11095-025-03987-0
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1007/s11095-025-03987-0
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Author Notes:Toshiki Kurosawa, Sumio Ohtsuki, Hiroshi Ishikawa, Horst Schroten, Christian Schwerk, Yoshiyuki Kubo, Yoshiharu Deguchi
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Summary:Human choroid plexus papilloma (HIBCPP) cells derived from choroid plexus papilloma in the lateral ventricle are considered suitable model cells for the blood-cerebrospinal fluid barrier (BCSFB). Therefore, in this study, the transporters expressed in HIBCPP cells were identified, and the functions of representative transporters were evaluated.
Item Description:Gesehen am 12.01.2026
Physical Description:Online Resource
ISSN:1573-904X
DOI:10.1007/s11095-025-03987-0

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