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Progression of QRS duration: a potential surrogate marker of survival in ATTRwt amyloidosis patients

In wild-type transthyretin amyloidosis (ATTRwt), the deposition of transthyretin in the myocardium leads to progressive heart failure. However, little is known about the short-term natural progression of this disease and potential predictors of outcome.

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Bibliographic Details
Main Authors: Hein, Selina (Author) , Siepen, Fabian aus dem (Author) , Zierleyn, Sonja M. (Author) , Knoll, Maximilian (Author) , Katus, Hugo (Author) , Frey, Norbert (Author) , Kristen, Arnt (Author)
Format: Article (Journal)
Language:English
Published: 20 October 2025
In: Orphanet journal of rare diseases
Year: 2025, Volume: 20, Issue: 1, Pages: 1-9
ISSN:1750-1172
DOI:10.1186/s13023-025-04078-4
Online Access:Resolving-System, kostenfrei, Volltext: https://doi.org/10.1186/s13023-025-04078-4
Verlag, kostenfrei, Volltext: https://link.springer.com/article/10.1186/s13023-025-04078-4
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Author Notes:Selina Hein, Fabian aus dem Siepen, Sonja M. Zierleyn, Maximilian Knoll, Hugo A. Katus, Norbert Frey, Arnt V. Kristen
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Summary:In wild-type transthyretin amyloidosis (ATTRwt), the deposition of transthyretin in the myocardium leads to progressive heart failure. However, little is known about the short-term natural progression of this disease and potential predictors of outcome.
Item Description:Gesehen am 14.01.2026
Physical Description:Online Resource
ISSN:1750-1172
DOI:10.1186/s13023-025-04078-4

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