Feasibility of different meningioma delineation approaches on (18F)SiTATE PET/CT imaging

Somatostatin receptor (SSTR)-targeted PET is valuable for meningioma imaging due to high SSTR expression. [18F]SiTATE, a novel tracer, is not only promising for imaging neuroendocrine tumors but also for meningiomas. Standardized delineation methods on [18F]SiTATE PET are lacking. This study correla...

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Main Authors: Kunte, Sophie Carina (Author) , Unterrainer, Lena M. (Author) , Lindner, Simon (Author) , Holzgreve, Adrien (Author) , Kunz, Wolfgang G. (Author) , Winkelmann, Michael (Author) , Nitschmann, Alexander (Author) , Jurkschat, Klaus (Author) , Wängler, Carmen (Author) , Wängler, Björn (Author) , Schirrmacher, Ralf (Author) , Belka, Claus (Author) , Thon, Niklas (Author) , Schichor, Christian (Author) , Bartenstein, Peter (Author) , Unterrainer, Marcus (Author)
Format: Article (Journal)
Language:English
Published: December 2025
In: Discover oncology
Year: 2025, Volume: 16, Issue: 1, Pages: 1-13
ISSN:2730-6011
DOI:10.1007/s12672-025-04079-6
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.1007/s12672-025-04079-6
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Author Notes:Sophie Carina Kunte, Lena M. Unterrainer, Simon Lindner, Adrien Holzgreve, Wolfgang G. Kunz, Michael Winkelmann, Alexander Nitschmann, Klaus Jurkschat, Carmen Wängler, Björn Wängler, Ralf Schirrmacher, Claus Belka, Niklas Thon, Christian Schichor, Peter Bartenstein and Marcus Unterrainer
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Summary:Somatostatin receptor (SSTR)-targeted PET is valuable for meningioma imaging due to high SSTR expression. [18F]SiTATE, a novel tracer, is not only promising for imaging neuroendocrine tumors but also for meningiomas. Standardized delineation methods on [18F]SiTATE PET are lacking. This study correlates CT-based volumes with PET-based delineation approaches to identify a threshold for standardized [18F]SiTATE PET volume assessment.
Item Description:Online veröffentlicht: 14. November 2025
Im Titel ist (18F) in eckigen Klammern geschrieben und hochgestellt
Gesehen am 29.01.2026
Physical Description:Online Resource
ISSN:2730-6011
DOI:10.1007/s12672-025-04079-6