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68Ga-FAPI PET/CT for non-invasive characterization and activity assessment of ulcerative colitis and Crohn´s disease

Inflammatory Bowel Diseases (IBD) comprise ulcerative colitis (UC) and Crohn’s disease (CD). Management of IBD requires assessment of disease activity, severity, extent and complications. Here, we describe the signal behavior of both CD and UC in 68Gallium- fibroblast activation protein inhibitor-ba...

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Main Authors: Debus, Josefin (Author) , von Götze, Isabelle (Author) , Brandt, Johannes (Author) , Ehehalt, Robert (Author) , Spektor, Anna-Maria (Author) , Mildenberger, Philipp (Author) , Gauss, Annika (Author) , Lang, Matthias (Author) , Glatting, Frederik M. (Author) , Schreckenberger, Mathias (Author) , Kalla, Rahul (Author) , Haberkorn, Uwe (Author) , Röhrich, Manuel (Author)
Format: Article (Journal)
Language:English
Published: 02 January 2026
In: European journal of nuclear medicine and molecular imaging

ISSN:1619-7089
DOI:10.1007/s00259-025-07686-1
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.1007/s00259-025-07686-1
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Author Notes:Josefin Debus, Isabelle von Götze, Johannes Brandt, Robert Ehehalt, Anna-Maria Spektor, Philipp Mildenberger, Annika Gauss, Matthias Lang, Frederik M. Glatting, Mathias Schreckenberger, Rahul Kalla, Uwe Haberkorn, Manuel Röhrich
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Summary:Inflammatory Bowel Diseases (IBD) comprise ulcerative colitis (UC) and Crohn’s disease (CD). Management of IBD requires assessment of disease activity, severity, extent and complications. Here, we describe the signal behavior of both CD and UC in 68Gallium- fibroblast activation protein inhibitor-based radiopharmaceuticals-46-positron emission tomography (68Ga-FAPI-46-PET) and evaluate the potential of 68Ga-FAPI-46-PET for activity assessment in IBD.
Item Description:Im Titel ist die Zahl 68 hochgestellt
Gesehen am 05.02.2026
Physical Description:Online Resource
ISSN:1619-7089
DOI:10.1007/s00259-025-07686-1

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