The association between hourly systolic blood pressure variability and outcomes in patients with intracerebral hemorrhage is time-dependent: post-hoc analysis of the ATACH-2 trial

Systolic blood pressure (SBP) variability has been associated with an increase in rates of death or disability in patients with intracerebral hemorrhage (ICH). We analyzed data from the Antihypertensive Treatment of Acute Cerebral Hemorrhage (ATACH)-2 trial to determine whether the association betwe...

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Main Authors: Qureshi, Adnan (Author) , Baskett, William (Author) , Gomes, Joao A. (Author) , Lakhani, Pashmeen (Author) , Rabinstein, Alejandro A. (Author) , Rose, David Z. (Author) , Suarez, Jose I. (Author) , Steiner, Thorsten (Author) , Shyu, Chi-Ren (Author)
Format: Article (Journal)
Language:English
Published: 24 September 2025
In: Neurocritical care

ISSN:1556-0961
DOI:10.1007/s12028-025-02376-0
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1007/s12028-025-02376-0
Verlag, lizenzpflichtig, Volltext: https://link.springer.com/article/10.1007/s12028-025-02376-0
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Author Notes:Adnan I. Qureshi, William Baskett, Joao A. Gomes, Pashmeen Lakhani, Alejandro A. Rabinstein, David Z. Rose, Jose I. Suarez, Thorsten Steiner and Chi-Ren Shyu
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Summary:Systolic blood pressure (SBP) variability has been associated with an increase in rates of death or disability in patients with intracerebral hemorrhage (ICH). We analyzed data from the Antihypertensive Treatment of Acute Cerebral Hemorrhage (ATACH)-2 trial to determine whether the association between SBP variability and death or disability at 90 days is dependent on the time from randomization.
Item Description:Gesehen am 05.02.2026
Physical Description:Online Resource
ISSN:1556-0961
DOI:10.1007/s12028-025-02376-0